Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2'-chloro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
2'-fluoro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
2'-methoxy-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
2-chloro-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
2-cyano-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
2-fluoro-N'-(phenylsulfonyl)benzohydrazide | - |
Mus musculus | |
2-fluoro-N'-[(3-fluorophenyl)sulfonyl]benzohydrazide | - |
Mus musculus | |
2-fluoro-N'-[[3-(trifluoromethyl)phenyl]sulfonyl]benzohydrazide | - |
Mus musculus | |
2-hydroxy-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
3'-chloro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
3'-cyano-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
3'-fluoro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
3'-methoxy-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
3-(2-(2-fluorobenzoyl)hydrazinylsulfono)benzamide | - |
Mus musculus | |
3-amino-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
3-chloro-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
3-chloro-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
3-cyano-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
3-fluoro-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
3-methyl-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
4'-chloro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
4'-cyano-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
4'-fluoro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
4'-methoxy-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | - |
Mus musculus | |
4-amino-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
4-butoxy-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
4-chloro-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
4-cyano-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
4-hydroxy-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
CTX-0124143 | i.e. N'-(2-fluorobenzoyl)naphthalene-2-sulfonohydrazide | Mus musculus | |
N'-( 2-fluoro-[1,1'- biphenyl]-3-carbonyl)-benzenesulfonohydrazide | - |
Mus musculus | |
N'-(2,3-difluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(2,3-difluorobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(2-dluorobenzoyl)-4-methylbenzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluoro-3-(trifluoromethyl)benzoyl)-benzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluoro-3-(trifluoromethyl)benzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(2-fluoro-3-methoxybenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluoro-3-methylbenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluoro-3-methylbenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(2-fluoro-5-methylbenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(2-fluorobenzoyl)-2-methoxybenzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluorobenzoyl)-2-methylbenzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluorobenzoyl)-3-methoxybenzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluorobenzoyl)-3-methylbenzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-fluorobenzoyl)-4-methoxybenzenesulfonohydrazide | - |
Mus musculus | |
N'-(2-methoxybenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(2-methylbenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(2-phenylisonicotinoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-(1H-pyrazol-1-yl)benzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-(piperazin-1-yl)benzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-(pyridin-3-yl)benzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-(pyrimidin-5-yl)benzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-(thiophen-2-yl)benzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-(thiophen-3-yl)benzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-(trifluoromethoxy)benzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-(trifluoromethyl)benzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-acetylbenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-aminobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-chloro-2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-chloro-2-fluorobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-cyanobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-ethyl-2-fluorobenzoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(3-ethyl-2-fluorobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-fluorobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-isopropylbenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(3-methoxylbenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(4-(trifluoromethoxy)benzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(4-cyanobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(4-fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-benzenesulfonohydrazide | - |
Mus musculus | |
N'-(4-fluoro-[1,1'-biphenyl]-3-carbonyl)-benzenesulfonohydrazide | - |
Mus musculus | |
N'-(4-fluorobenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(4-methoxybenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(4-methylbenzoyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-(5-chloro-4-fluoro-[1,1'-biphenyl]-3-carbonyl)-benzenesulfonohydrazide | - |
Mus musculus | |
N'-(5-phenylnicotinoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(6-phenylpicolinoyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-(naphthalen-2-ylsulfonyl)benzohydrazide | - |
Mus musculus | |
N'-([1,1'-biphenyl]-3-carbonyl)benzenesulfonohydrazide | - |
Mus musculus | |
N'-([1,1'-biphenyl]-3-carbonyl)naphthalene-2-sulfonohydrazide | - |
Mus musculus | |
N'-benzoylbenzenesulfonohydrazide | - |
Mus musculus | |
N'-[(3-bromophenyl)sulfonyl]-2-fluorobenzohydrazide | - |
Mus musculus | |
N'-[(3-ethylphenyl)sulfonyl]-2-fluorobenzohydrazide | - |
Mus musculus | |
N'-[(4-bromophenyl)sulfonyl]-2-fluorobenzohydrazide | - |
Mus musculus | |
tert-butyl-(3-(2-(naphthalen-2-ylsulfono)hydrazinecarbonyl)-phenyl)carbamate | - |
Mus musculus | |
WM-1119 | - |
Mus musculus | |
WM-8014 | highly potent inhibitor, competitive inhibition with respect to acetyl-CoA | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8BZ21 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
HAT | - |
Mus musculus |
KAT6A | - |
Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000002 | - |
pH and temperature not specified in the publication | Mus musculus | WM-1119 | |
0.000008 | - |
pH and temperature not specified in the publication | Mus musculus | WM-8014 | |
0.000008 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(4-fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-benzenesulfonohydrazide | |
0.00001 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(5-chloro-4-fluoro-[1,1'-biphenyl]-3-carbonyl)-benzenesulfonohydrazide | |
0.000017 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(4-fluoro-[1,1'-biphenyl]-3-carbonyl)-benzenesulfonohydrazide | |
0.000043 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-chloro-2-fluorobenzoyl)naphthalene-2-sulfonohydrazide | |
0.000062 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-ethyl-2-fluorobenzoyl)naphthalene-2-sulfonohydrazide | |
0.000077 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluoro-3-(trifluoromethyl)benzoyl)naphthalene-2-sulfonohydrazide | |
0.00012 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluoro-3-methylbenzoyl)naphthalene-2-sulfonohydrazide | |
0.00013 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2,3-difluorobenzoyl)naphthalene-2-sulfonohydrazide | |
0.00013 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-chloro-2-fluorobenzoyl)benzenesulfonohydrazide | |
0.00016 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(thiophen-2-yl)benzoyl)benzenesulfonohydrazide | |
0.00023 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluoro-3-methylbenzoyl)benzenesulfonohydrazide | |
0.00027 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-( 2-fluoro-[1,1'- biphenyl]-3-carbonyl)-benzenesulfonohydrazide | |
0.00029 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-([1,1'-biphenyl]-3-carbonyl)benzenesulfonohydrazide | |
0.00039 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluoro-3-(trifluoromethyl)benzoyl)-benzenesulfonohydrazide | |
0.00046 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-[(4-bromophenyl)sulfonyl]-2-fluorobenzohydrazide | |
0.00049 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3-amino-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | |
0.00049 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluoro-3-methoxybenzoyl)benzenesulfonohydrazide | |
0.00052 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3-chloro-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.00058 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-ethyl-2-fluorobenzoyl)benzenesulfonohydrazide | |
0.00062 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2'-fluoro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.00074 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2,3-difluorobenzoyl)benzenesulfonohydrazide | |
0.00079 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3'-chloro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.00088 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-([1,1'-biphenyl]-3-carbonyl)naphthalene-2-sulfonohydrazide | |
0.00091 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluoro-5-methylbenzoyl)naphthalene-2-sulfonohydrazide | |
0.001 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-[(3-bromophenyl)sulfonyl]-2-fluorobenzohydrazide | |
0.001 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | CTX-0124143 | |
0.0011 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluorobenzoyl)-3-methoxybenzenesulfonohydrazide | |
0.0013 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3-fluoro-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | |
0.0014 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3-methyl-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.0017 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3-chloro-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | |
0.0018 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2-fluoro-N'-(phenylsulfonyl)benzohydrazide | |
0.0021 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-fluorobenzoyl)naphthalene-2-sulfonohydrazide | |
0.0028 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(trifluoromethoxy)benzoyl)naphthalene-2-sulfonohydrazide | |
0.0034 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3'-cyano-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.0035 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluorobenzoyl)-3-methylbenzenesulfonohydrazide | |
0.004 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4'-chloro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.0041 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2-fluoro-N'-[(3-fluorophenyl)sulfonyl]benzohydrazide | |
0.0042 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.0044 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2-fluoro-N'-[[3-(trifluoromethyl)phenyl]sulfonyl]benzohydrazide | |
0.0057 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2-fluoro-N'-[(3-fluorophenyl)sulfonyl]benzohydrazide | |
0.0062 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluorobenzoyl)-2-methylbenzenesulfonohydrazide | |
0.0067 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-benzoylbenzenesulfonohydrazide | |
0.0071 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2'-chloro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.0073 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2-cyano-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | |
0.0074 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(piperazin-1-yl)benzoyl)benzenesulfonohydrazide | |
0.0078 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-isopropylbenzoyl)naphthalene-2-sulfonohydrazide | |
0.0082 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2'-methoxy-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.009 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3'-methoxy-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.0095 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4'-fluoro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.011 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3'-fluoro-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.011 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(trifluoromethyl)benzoyl)naphthalene-2-sulfonohydrazide | |
0.012 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3-(2-(2-fluorobenzoyl)hydrazinylsulfono)benzamide | |
0.012 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | CTX-0124143 | |
0.0125 | - |
IC50 above 0.0125 mM, in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4-amino-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | |
0.0125 | - |
IC50 above 0.0125 mM, in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4-cyano-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | |
0.0125 | - |
IC50 above 0.0125 mM, in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-dluorobenzoyl)-4-methylbenzenesulfonohydrazide | |
0.0125 | - |
IC50 above 0.0125 mM, in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluorobenzoyl)-4-methoxybenzenesulfonohydrazide | |
0.013 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(thiophen-3-yl)benzoyl)benzenesulfonohydrazide | |
0.014 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 3-cyano-N'-(2-fluorobenzoyl)benzenesulfonohydrazide | |
0.017 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-fluorobenzoyl)-2-methoxybenzenesulfonohydrazide | |
0.018 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(6-phenylpicolinoyl)benzenesulfonohydrazide | |
0.018 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-methoxylbenzoyl)naphthalene-2-sulfonohydrazide | |
0.019 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-methylbenzoyl)naphthalene-2-sulfonohydrazide | |
0.019 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-phenylisonicotinoyl)benzenesulfonohydrazide | |
0.019 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-[(3-ethylphenyl)sulfonyl]-2-fluorobenzohydrazide | |
0.019 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-aminobenzoyl)naphthalene-2-sulfonohydrazide | |
0.022 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(5-phenylnicotinoyl)benzenesulfonohydrazide | |
0.024 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-cyanobenzoyl)naphthalene-2-sulfonohydrazide | |
0.0258 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4'-methoxy-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.029 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(pyrimidin-5-yl)benzoyl)benzenesulfonohydrazide | |
0.03 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4-hydroxy-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.03 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(4-methylbenzoyl)naphthalene-2-sulfonohydrazide | |
0.041 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4'-cyano-N'-(phenylsulfonyl)biphenyl-3-carbohydrazide | |
0.042 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(2-methoxybenzoyl)naphthalene-2-sulfonohydrazide | |
0.049 | - |
in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2-hydroxy-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.06 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4-chloro-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.071 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | tert-butyl-(3-(2-(naphthalen-2-ylsulfono)hydrazinecarbonyl)-phenyl)carbamate | |
0.12 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(4-fluorobenzoyl)naphthalene-2-sulfonohydrazide | |
0.12 | - |
in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(4-methoxybenzoyl)naphthalene-2-sulfonohydrazide | |
0.125 | - |
IC50 above 0.125 mM, in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(1H-pyrazol-1-yl)benzoyl)benzenesulfonohydrazide | |
0.125 | - |
IC50 above 0.125 mM, in the presence of 0.0004 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-(pyridin-3-yl)benzoyl)benzenesulfonohydrazide | |
0.125 | - |
IC50 above 0.125 mM, in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 2-chloro-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.125 | - |
IC50 above 0.125 mM, in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | 4-butoxy-N'-(naphthalen-2-ylsulfonyl)benzohydrazide | |
0.125 | - |
IC50 above 0.125 mM, in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(3-acetylbenzoyl)naphthalene-2-sulfonohydrazide | |
0.125 | - |
IC50 above 0.125 mM, in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(4-(trifluoromethoxy)benzoyl)naphthalene-2-sulfonohydrazide | |
0.125 | - |
IC50 above 0.125 mM, in the presence of 0.015 mM acetyl-CoA, pH and temperature not specified in the publication | Mus musculus | N'-(4-cyanobenzoyl)naphthalene-2-sulfonohydrazide |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme inhibition induces cellular senescence | Mus musculus |