Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mesenchymal stem cell | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
Gcn5 | general control nonderepressible 5 | Mus musculus |
HAT | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | the enzyme expression is decreased significantly in the bone tissue sections of ovariectomized mice or aged mice | down |
General Information | Comment | Organism |
---|---|---|
malfunction | knockdown of the enzyme inhibits differentiation of mesenchymal stem cells into osteoblast cells. The impaired osteogenic differentiation by enzyme knockdown is blocked by inhibition of nuclear factor kappaB | Mus musculus |
metabolism | the enzyme regulates osteogenic differentiation of mesenchymal stem cells by inhibiting nuclear factor kappaB. The enzyme represses nuclear factor kappa B-dependent transcription and inhibits the nuclear factor kappaB signaling pathway | Mus musculus |