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Literature summary for 2.3.1.45 extracted from
- Assays of sialate-O-acetyltransferases and sialate-O-acetylesterases (2008), Glycoconj. J., 26, 935-944.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| DTT | - |
Campylobacter jejuni |  |
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | methods for assaying the activity of sialate-O-acetyltransferases are presented | Cavia porcellus |
| analysis | methods for assaying the activity of sialate-O-acetyltransferases are presented | Escherichia coli |
| analysis | methods for assaying the activity of sialate-O-acetyltransferases are presented | Rattus norvegicus |
| analysis | methods for assaying the activity of sialate-O-acetyltransferases are presented | Bos taurus |
| analysis | methods for assaying the activity of sialate-O-acetyltransferases are presented | Campylobacter jejuni |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
- |
Campylobacter jejuni |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Cavia porcellus | 16020 | - |
| membrane | - |
Rattus norvegicus | 16020 | - |
| membrane | - |
Bos taurus | 16020 | - |
| microsome | - |
Cavia porcellus | - |
- |
| microsome | - |
Rattus norvegicus | - |
- |
| microsome | - |
Bos taurus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | assay with 25 mM | Escherichia coli | |
| Mg2+ | 10 mM | Campylobacter jejuni | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + N-acetylneuraminate | Cavia porcellus | - |
CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | Escherichia coli | - |
CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | Rattus norvegicus | - |
CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | Bos taurus | - |
CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | Campylobacter jejuni | - |
CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Campylobacter jejuni | - |
- |
- |
| Cavia porcellus | - |
guinea pig | - |
| Escherichia coli | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| affinity purified | Escherichia coli |
| affinity purified | Campylobacter jejuni |
| affinity-purified | Escherichia coli |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Cavia porcellus | - |
| liver | - |
Rattus norvegicus | - |
| submandibular gland | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + colominic acid | - |
Escherichia coli | CoA + ? | - |
? | |
| acetyl-CoA + N-acetylneuraminate | - |
Cavia porcellus | CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | - |
Escherichia coli | CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | - |
Rattus norvegicus | CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | - |
Bos taurus | CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + N-acetylneuraminate | - |
Campylobacter jejuni | CoA + N-acetyl-7-O-acetylneuraminate | - |
? | |
| acetyl-CoA + Neu5Acalpha2-8Neu5Acalpha2-3Galbeta1-4Glc-[6-(5-fluorescein-carboxamido)-hexanic acid succimidylester] | the O-acetylation reaction is also followed by real time NMR spectroscopy showing preferred incorporation of the acetyl group at C-9 of alpha2-8-linked Sia | Campylobacter jejuni | CoA + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sialate O-acetyltransferase | - |
Escherichia coli |
| sialate O-acetyltransferase | - |
Campylobacter jejuni |
| sialate-O-acetyltransferase | - |
Cavia porcellus |
| sialate-O-acetyltransferase | - |
Escherichia coli |
| sialate-O-acetyltransferase | - |
Rattus norvegicus |
| sialate-O-acetyltransferase | - |
Bos taurus |
| sialate-O-acetyltransferase | - |
Campylobacter jejuni |
| SOAT | - |
Cavia porcellus |
| SOAT | - |
Escherichia coli |
| SOAT | - |
Rattus norvegicus |
| SOAT | - |
Bos taurus |
| SOAT | - |
Campylobacter jejuni |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Escherichia coli |
| 25 | - |
activity assay | Escherichia coli |
| 37 | - |
assay at | Campylobacter jejuni |
| 37 | - |
activity assay | Cavia porcellus |
| 37 | - |
activity assay | Rattus norvegicus |
| 37 | - |
activity assay | Bos taurus |
| 37 | - |
activity assay | Campylobacter jejuni |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
assay at | Campylobacter jejuni |
| 6.5 | - |
activity assay | Cavia porcellus |
| 6.5 | - |
activity assay | Rattus norvegicus |
| 6.5 | - |
activity assay | Bos taurus |
| 6.5 | - |
activity assay | Campylobacter jejuni |
| 7.5 | - |
assay at | Escherichia coli |
| 7.5 | - |
activity assay | Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| acetyl-CoA | - |
Cavia porcellus | |
| acetyl-CoA | - |
Escherichia coli | |
| acetyl-CoA | - |
Rattus norvegicus | |
| acetyl-CoA | - |
Bos taurus | |
| acetyl-CoA | - |
Campylobacter jejuni | |
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