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Literature summary for 2.3.1.43 extracted from

  • Dobiasova, M.
    Atherogenic impact of lecithin-cholesterol acyltransferase and its relation to cholesterol esterification rate in HDL (FER(HDL)) and AIP [log(TG/HDL-C)] biomarkers the butterfly effect? (2017), Physiol. Res., 66, 193-203 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information high-density lipoprotein subfraction 2 functions as an inhibitor of the cholesterol esterification reaction Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphatidylcholine + a sterol Homo sapiens
-
1-acylglycerophosphocholine + a sterol ester
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P04180
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information high-density lipoprotein subfraction 3 functions as highly effective substrate Homo sapiens ?
-
-
phosphatidylcholine + a sterol
-
Homo sapiens 1-acylglycerophosphocholine + a sterol ester
-
?
phosphatidylcholine + cerebrosterol
-
Homo sapiens 1-acylglycerophosphocholine + cerebrosteryl ester
-
?
phosphatidylcholine + cholesterol
-
Homo sapiens 1-acylglycerophosphocholine + cholesteryl ester
-
?

Subunits

Subunits Comment Organism
? x * 67000, calculated from amino acid sequence Homo sapiens

Synonyms

Synonyms Comment Organism
LCAT
-
Homo sapiens
lecithin-cholesterol acyltransferase
-
Homo sapiens