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Literature summary for 2.3.1.43 extracted from

  • Soupene, E.; Borja, M.S.; Borda, M.; Larkin, S.K.; Kuypers, F.A.
    Featured article alterations of lecithin cholesterol acyltransferase activity and apolipoprotein A-I functionality in human sickle blood (2016), Exp. Biol. Med. (Maywood), 241, 1933-1942 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.43

Organism

Organism UniProt Comment Textmining
Homo sapiens P04180
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + cholesterol
-
 Homo sapiens 1-acylglycerophosphocholine + cholesterol ester
-
 ?

Synonyms

Synonyms Comment Organism
LCAT
-
 Homo sapiens
lecithin cholesterol acyltransferase
-
 Homo sapiens
lecithin:cholesterol acyl-transferase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens in blood plasma from sickle cell disease patients, the enzyme concentrations are lower than in normal blood down

General Information

General Information Comment Organism
malfunction the enzyme activity is reduced in sickle cell disease Homo sapiens