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Literature summary for 2.3.1.43 extracted from

  • Lee, R.G.; Shah, R.; Sawyer, J.K.; Hamilton, R.L.; Parks, J.S.; Rudel, L.L.
    ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice (2005), J. Lipid Res., 46, 1205-1212.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information LCAT deficiency significantly decreases the cholesteryl ester percentage and significantly increases the phospholipid percentage of LDL, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus LCAT adds cholesteryl ester to LDL in mice and is important in remodeling VLDL to LDL, LCAT deficiency significantly decreases the cholesteryl ester percentage and significantly increases the phospholipid percentage of LDL, overview ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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lipid accumulation in wild-type and LCAT-/- mutant strains, overview Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information LCAT adds cholesteryl ester to LDL in mice and is important in remodeling VLDL to LDL, LCAT deficiency significantly decreases the cholesteryl ester percentage and significantly increases the phospholipid percentage of LDL, overview Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
LCAT
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Mus musculus