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Literature summary for 2.3.1.43 extracted from

  • Demeester, N.; Castro, G.; Desrumaux, C.; De Geitere, C.; Fruchart, J.C.; Santens, P.; Mulleners, E.; Engelborghs, S.; De Deyn, P.P.; Vandekerckhove, J.; Rosseneu, M.; Labeur, C.
    Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease (2000), J. Lipid Res., 41, 963-974.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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patients with Alzheimer's disease have lower LCAT activity in cerebrospinal fluid Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine + cholesterol activity assay method based on this reaction Homo sapiens cholesteryl-1-pyrenebutyrate + lysophosphatidylcholine
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?
phosphatidylcholine + sterol
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Homo sapiens 1-acylglycerophosphocholine + sterol ester
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?