Literature summary for 2.3.1.41 extracted from

Bao, W.; Sheldon, P.J.; Hutchinson, C.R.
Purification and properties of the Streptomyces peucetius DpsC beta-ketoacyl:acyl carrier protein synthase III that specifies the propionate-starter unit for type II polyketide biosynthesis (1999), Biochemistry, 38, 9752-9757.

Search for more literature for 2.3.1.41

Cloned(Commentary)

Cloned (Comment)	Organism
expression of synthase III-like polyketid synthase in Streptomyces lividans	Streptomyces peucetius

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
38000	-	synthase III-like polyketid synthase, gel filtration, amino acid sequence determination	Streptomyces peucetius

Organism

Organism	UniProt	Comment	Textmining
Streptomyces peucetius	-	synthase III-like activity	-

Purification (Commentary)

Purification (Comment)	Organism
synthase III-like polyketid synthase recombinant from Streptomyces lividans	Streptomyces peucetius

Reaction

Reaction	Comment	Organism	Reaction ID
an acyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] = a 3-oxoacyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]	acetylation of the synthase III-like polyketid synthase at Ser118	Streptomyces peucetius	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
propionyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein]	absolutely specific for	Streptomyces peucetius	beta-ketopentanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * 38000, synthase III-like polyketid synthase, SDS-PAGE	Streptomyces peucetius

Synonyms

Synonyms	Comment	Organism
DpsC	-	Streptomyces peucetius
More	gene DpsC, encoding apolyketide synthase, exhibits also beta-keto-[acyl-carrier-protein] synthase III activity, which is restricted for propionyl-[acyl-carrier-protein] as the only [acyl-carrier-protein]-substrate	Streptomyces peucetius

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Release 2023.1 (January 2023)