Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-amino-2,3-dideoxy-3-fluoro-alpha-D-glucopyranosyl phosphate | inhibition of acetyltransferase activity. Compound cannot substitute the natural substrate GlcN-1-P. Uncompetitive inhibition, compound interacts with the enzymesubstrate complex. | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
bifunctional glucosamine-1-phosphate acetyltransferase/N-acetylglucosamine-1-phosphate uridyltransferase | - |
Synonyms | Comment | Organism |
---|---|---|
GlmU | - |
Mycobacterium tuberculosis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
18.7 | - |
2-amino-2,3-dideoxy-3-fluoro-alpha-D-glucopyranosyl phosphate | pH 7.5, 37°C | Mycobacterium tuberculosis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
12.84 | - |
pH 7.5, 37°C | Mycobacterium tuberculosis | 2-amino-2,3-dideoxy-3-fluoro-alpha-D-glucopyranosyl phosphate |