Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ClpX | the mitochondrial AAA+ unfoldase ClpX participates in both heme-dependent degradation of the enzyme and its activation | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + glycine | Homo sapiens | - |
5-aminolevulinate + CoA + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythroid cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + glycine | - |
Homo sapiens | 5-aminolevulinate + CoA + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ALAS | - |
Homo sapiens |
delta-aminolevulinate synthase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the presence of low-activity mitochondrial AAA+ unfoldase CLPX increases the posttranslational stability of the enzyme, causing increased protein level | up |