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Literature summary for 2.3.1.306 extracted from
- The route of lysine breakdown in Candida tropicalis (1991), FEMS Microbiol. Lett., 66, 209-213 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + L-lysine | Candida tropicalis | - |
CoA + N6-acetyl-L-lysine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida tropicalis | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.045 | - |
pH 8.5, 25°C | Candida tropicalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + L-lysine | - |
Candida tropicalis | CoA + N6-acetyl-L-lysine | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Candida tropicalis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
assay at | Candida tropicalis |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Candida tropicalis | expression is induced after growth in defined medium on L-lysine as sole nitrogen source | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | L-lysine is degraded in Candida tropicalis via N6-acetyllysine, 5-acetamidovalerate and 5-aminovalerate, both nitrogen atoms being removed by transamination | Candida tropicalis |
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Release 2023.1 (January 2023)
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