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Literature summary for 2.3.1.289 extracted from

  • Sugimoto, Y.; Ding, L.; Ishida, K.; Hertweck, C.
    Rational design of modular polyketide synthases morphing the aureothin pathway into a luteoreticulin assembly line (2014), Angew. Chem. Int. Ed. Engl., 53, 1560-1564 .
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
synthesis engineering of the modular (type I) Aur polyketide synthase into a synthase that generates luteoreticulin unsing genes from a single biosynthesis gene cluster to design the artificial pathway Streptomyces thioluteus

Organism

Organism UniProt Comment Textmining
Streptomyces thioluteus Q70KH8 and Q70KH5 and Q70KH4 Q70KH8 i.e. subunit AurA, Q70KH5 i.e. subunit AurB, Q70KH4 i.e. subunit AurC
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Streptomyces thioluteus HKI-227 Q70KH8 and Q70KH5 and Q70KH4 Q70KH8 i.e. subunit AurA, Q70KH5 i.e. subunit AurB, Q70KH4 i.e. subunit AurC
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