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Literature summary for 2.3.1.280 extracted from

  • Hove-Jensen, B.; McSorley, F.R.; Zechel, D.L.
    Catabolism and detoxification of 1-aminoalkylphosphonic acids N-acetylation by the phnO gene product (2012), PLoS ONE, 7, e46416 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.280

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + (aminomethyl)phosphonate Escherichia coli the physiological role of N-acetylation by phnO-specified aminoalkylphosphonate N-acetyltransferase is to detoxify (S)-1-aminoethylphosphonate, an analog of D-alanine, and to prepare (S)-1-aminoethylphosphonate and aminomethylphosphonate for utilization of the phosphorus-containing moiety CoA + (acetamidomethyl)phosphonate
-
 ?
acetyl-CoA + (S)-1-aminoethylphosphonate Escherichia coli the physiological role of N-acetylation by phnO-specified aminoalkylphosphonate N-acetyltransferase is to detoxify (S)-1-aminoethylphosphonate, an analog of D-alanine, and to prepare (S)-1-aminoethylphosphonate and aminomethylphosphonate for utilization of the phosphorus-containing moiety CoA + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P16691 in strain HO2735 the lacIq-specified repressor served to repress transcription of genes harbored in the pUHE23-2 vector
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + (aminomethyl)phosphonate
-
 Escherichia coli CoA + (acetamidomethyl)phosphonate
-
 ?
acetyl-CoA + (aminomethyl)phosphonate the physiological role of N-acetylation by phnO-specified aminoalkylphosphonate N-acetyltransferase is to detoxify (S)-1-aminoethylphosphonate, an analog of D-alanine, and to prepare (S)-1-aminoethylphosphonate and aminomethylphosphonate for utilization of the phosphorus-containing moiety Escherichia coli CoA + (acetamidomethyl)phosphonate
-
 ?
acetyl-CoA + (S)-1-aminoethylphosphonate
-
 Escherichia coli CoA + ?
-
 ?
acetyl-CoA + (S)-1-aminoethylphosphonate the physiological role of N-acetylation by phnO-specified aminoalkylphosphonate N-acetyltransferase is to detoxify (S)-1-aminoethylphosphonate, an analog of D-alanine, and to prepare (S)-1-aminoethylphosphonate and aminomethylphosphonate for utilization of the phosphorus-containing moiety Escherichia coli CoA + ?
-
 ?
acetyl-CoA + 2-aminoethylphosphonate
-
 Escherichia coli CoA + ?
-
 ?
acetyl-CoA + 3-aminopropylphosphonate
-
 Escherichia coli CoA + ?
-
 ?

Synonyms

Synonyms Comment Organism
aminoalkylphosphonate N-acetyltransferase
-
 Escherichia coli
phnO
-
 Escherichia coli

General Information

General Information Comment Organism
physiological function the physiological role of N-acetylation by phnO-specified aminoalkylphosphonate N-acetyltransferase is to detoxify (S)-1-aminoethylphosphonate, an analog of D-alanine, and to prepare (S)-1-aminoethylphosphonate and aminomethylphosphonate for utilization of the phosphorus-containing moiety Escherichia coli