Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | 2 mM, 80% inhibition | Sulfurisphaera tokodaii | |
Zn2+ | 2 mM, 75% inhibition | Sulfurisphaera tokodaii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.63 | - |
acetyl-CoA | pH 7.5, 80°C | Sulfurisphaera tokodaii | |
1.71 | - |
alpha-D-galactosamine 1-phosphate | pH 7.5, 80°C | Sulfurisphaera tokodaii |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 2 mM, enhances galactosamine-1-phosphate N-acetyltransferase activity 2.1fold | Sulfurisphaera tokodaii | |
Co2+ | 2 mM, enhances galactosamine-1-phosphate N-acetyltransferase activity 1.2fold | Sulfurisphaera tokodaii | |
Mg2+ | 2 mM, enhances galactosamine-1-phosphate N-acetyltransferase activity 1.4fold | Sulfurisphaera tokodaii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sulfurisphaera tokodaii | Q975F9 | - |
- |
Sulfurisphaera tokodaii 7 | Q975F9 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Sulfurisphaera tokodaii |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
38.4 | - |
pH 7.5, 80°C, substrates: acetyl-CoA + alpha-D-galactosamine 1-phosphate | Sulfurisphaera tokodaii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + alpha-D-galactosamine 1-phosphate | no activity with alpha-D-glucosamine 6-phosphate | Sulfurisphaera tokodaii | CoA + N-acetyl-alpha-D-galactosamine 1-phosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
80 | - |
assay at | Sulfurisphaera tokodaii |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
69.7 | - |
alpha-D-galactosamine 1-phosphate | pH 7.5, 80°C | Sulfurisphaera tokodaii |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Sulfurisphaera tokodaii |
General Information | Comment | Organism |
---|---|---|
physiological function | because the multifunctional ST0452 protein is capable of catalyzing the last two reactions (Ec 2.3.1.157 and EC 2.7.7.23 (UDP-N-acetylglucosamine diphosphorylase)) of the bacteria-type four-step biosynthesis pathway of UDP-alpha-D-glucosamine from fructose 6-phosphate, the ST0452 protein plays an important role for the bacteria-type UDP-alpha-D-glucosamine biosynthesis pathway in this archaeon | Sulfurisphaera tokodaii |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
40.8 | - |
alpha-D-galactosamine 1-phosphate | pH 7.5, 80°C | Sulfurisphaera tokodaii |