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Literature summary for 2.3.1.260 extracted from
- In vitro analysis of type II polyketide synthase (2009), Methods Enzymol., 459, 367-393.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Streptomyces coelicolor |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| malonamoyl-[OxyC acyl-carrier protein] + malonyl-CoA | Streptomyces coelicolor | - |
18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC acyl-carrier protein] + CO2 + CoA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces coelicolor | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA agarose column chromatography, amylose resin affinity chromatography, and Superdex 200 gel filtration | Streptomyces coelicolor |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| malonamoyl-[OxyC acyl-carrier protein] + malonyl-CoA | - |
Streptomyces coelicolor | 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC acyl-carrier protein] + CO2 + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| octaketide minimal PKS | - |
Streptomyces coelicolor |
| type II PKS | - |
Streptomyces coelicolor |
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Release 2023.1 (January 2023)
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