Cloned (Comment) | Organism |
---|---|
expression in CHO cells | Homo sapiens |
expression in CHO cells | Chlorocebus aethiops |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
celludinone A1 | an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay; an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay | Chlorocebus aethiops | |
celludinone A1 | an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay; an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay | Homo sapiens | |
celludinone A2 | an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay; an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay | Chlorocebus aethiops | |
celludinone A2 | an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay; an indanone produced by Talaromyces cellulolyticus BF-0307, inhibits the sterol O-acyltransferase 1 and 2 isozymes in a cell-based assay | Homo sapiens | |
celludinone B | an indanone produced by Talaromyces cellulolyticus BF-0307, selectively inhibits the SOAT2 isoform; an indanone produced by Talaromyces cellulolyticus BF-0307, selectively inhibits the SOAT2 isoform | Chlorocebus aethiops | |
celludinone B | an indanone produced by Talaromyces cellulolyticus BF-0307, selectively inhibits the SOAT2 isoform; an indanone produced by Talaromyces cellulolyticus BF-0307, selectively inhibits the SOAT2 isoform | Homo sapiens | |
FD-549 | benzophenone inhibitor; benzophenone inhibitor | Chlorocebus aethiops | |
FD-549 | benzophenone inhibitor; benzophenone inhibitor | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Chlorocebus aethiops | O77759 | isoform SOAT2 | - |
Chlorocebus aethiops | O77760 | isoform SOAT1 | - |
Homo sapiens | O75908 | - |
- |
Homo sapiens | P35610 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Soat2 | - |
Chlorocebus aethiops |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000069 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | celludinone B | |
0.00015 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | celludinone B | |
0.00068 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | FD-549 | |
0.00091 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | FD-549 | |
0.0028 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | celludinone B | |
0.0029 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | celludinone B | |
0.0048 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | celludinone A1 | |
0.0052 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | FD-549 | |
0.0061 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | celludinone A2 | |
0.008 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | celludinone A1 | |
0.0088 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | celludinone A1 | |
0.0099 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | FD-549 | |
0.012 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | celludinone A1 | |
0.013 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | celludinone A2 | |
0.015 | - |
cell-based assay, 37°C, pH not specified in the publication | Homo sapiens | celludinone A2 | |
0.015 | - |
cell-based assay, 37°C, pH not specified in the publication | Chlorocebus aethiops | celludinone A2 |