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Literature summary for 2.3.1.26 extracted from

  • Taketani, S.; Nishino, T.; Katsuki, H.
    Characterization of sterol-ester synthetase in Saccharomyces cerevisiae (1979), Biochim. Biophys. Acta, 575, 148-155.
    View publication on PubMed
Search for more literature for 2.3.1.26

Inhibitors

Inhibitors Comment Organism Structure
acetone about 40% inhibition at a final concentration of 1% v/v Saccharomyces cerevisiae
butanol about 40% inhibition at a final concentration of 1% v/v Saccharomyces cerevisiae
ethanol about 40% inhibition at a final concentration of 1% v/v Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.06
-
 cholesterol with oleoyl-CoA Saccharomyces cerevisiae
0.069
-
 oleoyl-CoA
-
 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Saccharomyces cerevisiae
-
-
spheroplast
-
 Saccharomyces cerevisiae
-
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + cholesterol 16% of the activity with oleoyl-CoA Saccharomyces cerevisiae CoA + cholesteryl acetate
-
 ?
acyl-CoA + cholesterol acyl-CoA derivatives can be replaced by ATP, Mg2+, CoA and fatty acids, in-situ production of acyl-CoA Saccharomyces cerevisiae CoA + cholesterol ester
-
 ?
lauroyl-CoA + cholesterol 62% of the activity with oleoyl-CoA Saccharomyces cerevisiae CoA + cholesteryl laurate
-
 ?
additional information the enzyme has a broad substrate specificity for sterols and acyl-CoAs Saccharomyces cerevisiae ?
-
 ?
myristoyl-CoA + cholesterol 37% of the activity with oleoyl-CoA Saccharomyces cerevisiae CoA + cholesteryl myristate
-
 ?
oleoyl-CoA + cholesterol highest activity Saccharomyces cerevisiae CoA + cholesteryl oleate
-
 ?
oleoyl-CoA + episterol 62% of the activity with cholesterol Saccharomyces cerevisiae CoA + episteryl oleate
-
 ?
oleoyl-CoA + ergosterol 147% of the activity with cholesterol Saccharomyces cerevisiae CoA + ergosteryl oleate
-
 ?
oleoyl-CoA + fecosterol 48% of the activity with cholesterol Saccharomyces cerevisiae CoA + fecosteryl oleate
-
 ?
oleoyl-CoA + lanosterol 65% of the activity with cholesterol Saccharomyces cerevisiae CoA + lanosteryl oleate
-
 ?
oleoyl-CoA + zymosterol 93% of the activity with cholesterol Saccharomyces cerevisiae CoA + zymosteryl oleate
-
 ?
palmitoleoyl-CoA + cholesterol 91% of the activity with oleoyl-CoA Saccharomyces cerevisiae CoA + cholesteryl palmitoleate
-
 ?
palmitoyl-CoA + cholesterol 47% of the activity with oleoyl-CoA Saccharomyces cerevisiae CoA + cholesteryl palmitate
-
 ?

Cofactor

Cofactor Comment Organism Structure
CoA required by the in-situ acyl-CoA production Saccharomyces cerevisiae