Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3)pLysS cells | Streptomyces coelicolor |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00358 | - |
malonyl-CoA | at pH 7.5 and 22°C | Streptomyces coelicolor |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43000 | - |
x * 43000, SDS-PAGE | Streptomyces coelicolor |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5 malonyl-CoA | Streptomyces coelicolor | - |
1,3,6,8-tetrahydroxynaphthalene + 5 CoA + 5 CO2 + H2O | - |
? | |
5 malonyl-CoA | Streptomyces coelicolor A3(2) | - |
1,3,6,8-tetrahydroxynaphthalene + 5 CoA + 5 CO2 + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces coelicolor | Q9FCA7 | - |
- |
Streptomyces coelicolor A3(2) | Q9FCA7 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni2+-affinity column chromatography | Streptomyces coelicolor |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5 malonyl-CoA | - |
Streptomyces coelicolor | 1,3,6,8-tetrahydroxynaphthalene + 5 CoA + 5 CO2 + H2O | - |
? | |
5 malonyl-CoA | - |
Streptomyces coelicolor A3(2) | 1,3,6,8-tetrahydroxynaphthalene + 5 CoA + 5 CO2 + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 43000, SDS-PAGE | Streptomyces coelicolor |
Synonyms | Comment | Organism |
---|---|---|
1,3,6,8-tetrahydroxynaphthalene synthase | - |
Streptomyces coelicolor |
PKS | - |
Streptomyces coelicolor |
SCO1206 | locus name | Streptomyces coelicolor |
THNS | - |
Streptomyces coelicolor |
type III polyketide synthase | - |
Streptomyces coelicolor |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.008 | - |
malonyl-CoA | at pH 7.5 and 22°C | Streptomyces coelicolor |