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Literature summary for 2.3.1.23 extracted from

  • Mansilla, F.; da Costa, K.A.; Wang, S.; Kruh?ffer, M.; Lewin, T.M.; Orntoft, T.F.; Coleman, R.A.; Birkenkamp-Demtroeder, K.
    Lysophosphatidylcholine acyltransferase 1 (LPCAT1) overexpression in human colorectal cancer (2009), J. Mol. Med., 87, 85-97.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.23

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 cell and SW-480 cell Homo sapiens

Protein Variants

Protein Variants Comment Organism
M427T naturally occuring mutation, does not significantly affect the activity or function Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8NF37
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colorectal adenocarcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
linoleoyl-CoA + 1-palmitoyl-2-lysophosphatidylcholine
-
 Homo sapiens CoA + 1-palmitoyl-2-linoleoylphosphatidylcholine
-
 ?
palmitoyl-CoA + 1-palmitoyl-2-lysophosphatidylcholine
-
 Homo sapiens CoA + 1,2-dipalmitoylphosphatidylcholine
-
 ?

Synonyms

Synonyms Comment Organism
LPCAT1
-
 Homo sapiens
lysophosphatidylcholine acyltransferase 1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens upregulated in colorectal adenocarcinomas (compared to normal mucosas) up