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Literature summary for 2.3.1.23 extracted from

  • Kerkhoff, C.; Habben, K.; Gehring, L.; Resch, K.; Kaever, V.
    Substrate specificity of acyl-CoA:lysophospholipid acyltransferase (LAT) from pig spleen (1998), Arch. Biochem. Biophys., 351, 220-226.
    View publication on PubMed
Search for more literature for 2.3.1.23

Activating Compound

Activating Compound Comment Organism Structure
ethanol integral membrane enzyme, 2% (v/v), 30% increase in activity Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
arachidonic acid 0.045 mM, 50% inhibition Sus scrofa
ethanol integral membrane enzyme, 10%, 20% inhibition Sus scrofa
oleic acid 0.08 mM, 50% inhibition Sus scrofa
palmitic acid 0.15 mM, 50% inhibition Sus scrofa
palmitoyl-CoA 0.2 mM, 50% inhibition Sus scrofa
palmitoyltrifluoromethylketone 0.15 mM, 50% inhibition Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Sus scrofa 16020
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial purification with palmitoyl-CoA-agarose affinity chromatography Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.042
-
 integral membrane enzyme, 1-palmitoyl-glycero-3-phosphocholine as substrate Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
acyl-CoA + 1-decanoyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-decanoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
acyl-CoA + 1-lauroyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-lauroyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
acyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine integral membrane enzyme, preferred acyl acceptors in descending order: 1-oleoyl-sn-glycero-3-phosphocholine, 1-stearoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-sn-glycero-3-phosphocholine, 1-myristoyl-sn-glycero-3-phosphocholine, 1-lauroyl-sn-glycero-3-phosphocholine and 1-decanoyl-sn-glycero-3-phosphocholine Sus scrofa CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?