Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli, N-terminally His6-tagged protein | Hypericum perforatum |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0013 | - |
benzoyl-CoA | pH 7.0, 35°C | Hypericum perforatum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3 malonyl-CoA + benzoyl-CoA | Hypericum perforatum | - |
4 CoA + 2,4,6-trihydroxybenzophenone + 3 CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hypericum perforatum | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endodermis | of the root | Hypericum perforatum | - |
exodermis | of the root | Hypericum perforatum | - |
root | localized to the exodermis and the endodermis | Hypericum perforatum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3 malonyl-CoA + 3-hydroxybenzoyl-CoA | 43.5% of the activity compared to benzoyl-CoA | Hypericum perforatum | 4 CoA + 2,3',4,6-tetrahydroxybenzophenone + 3 CO2 | - |
? | |
3 malonyl-CoA + benzoyl-CoA | - |
Hypericum perforatum | 4 CoA + 2,4,6-trihydroxybenzophenone + 3 CO2 | - |
? | |
3 malonyl-CoA + butyryl-CoA | formation of 36.8% 2,4,6-trihydroxybutyrophenone and 6-propyl-4-hydroxy-2-pyrone as side product | Hypericum perforatum | 4 CoA + 2,4,6-trihydroxybutyrophenone + 6-propyl-4-hydroxy-2-pyrone + 3 CO2 | - |
? | |
3 malonyl-CoA + isobutyryl-CoA | formation of 46.4% 2,4,6-trihydroxyisobutyrophenone and 34.2% 6-isopropyl-4-hydroxy-2-pyrone as side product | Hypericum perforatum | 4 CoA + 2,4,6-trihydroxyisobutyrophenone + 3 CO2 | - |
? | |
additional information | the enzyme does not accept 2-hydroxybenzoyl-CoA and 4-hydroxybenzoyl-CoA, acetyl-CoA, and CoA esters of cinnamic acids | Hypericum perforatum | ? | - |
- |
Synonyms | Comment | Organism |
---|---|---|
BPS | - |
Hypericum perforatum |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
35 | - |
- |
Hypericum perforatum |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0046 | - |
benzoyl-CoA | pH 7.0, 35°C | Hypericum perforatum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Hypericum perforatum |