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Literature summary for 2.3.1.22 extracted from

  • Hall, A.M.; Kou, K.; Chen, Z.; Pietka, T.A.; Kumar, M.; Korenblat, K.M.; Lee, K.; Ahn, K.; Fabbrini, E.; Klein, S.; Goodwin, B.; Finck, B.N.
    Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver (2012), J. Lipid Res., 53, 990-999.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens Q3SYC2
-
-
Homo sapiens Q86VF5
-
-
Homo sapiens Q96PD6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver expression of MOGAT2 does not correlate with enzymatic activity Homo sapiens
-
liver expression of MOGAT3 is correlated with enzymatic activity Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
decanoyl-CoA + 2-oleoylglycerol
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
MGAT
-
Homo sapiens
MOGAT1
-
Homo sapiens
MOGAT2
-
Homo sapiens
MOGAT3
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
additional information
-
assay carried out at room temperature Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Homo sapiens

Expression

Organism Comment Expression
Homo sapiens marked weight loss following gastric bypass surgery is associated with a significant reduction in MOGAT2 and MOGAT3 expression down

General Information

General Information Comment Organism
malfunction knockout of MOGAT3 attenuates MGAT activity in a liver-derived cell line Homo sapiens