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Literature summary for 2.3.1.22 extracted from

  • Yen, C.L.E.; Stone, S.J.; Cases, S.; Zhou, P.; Farese, R.V., Jr.
    Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase (2002), Proc. Natl. Acad. Sci. USA, 99, 8512-8517.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.22

Cloned(Commentary)

Cloned (Comment) Organism
expression of MGAT1 cDNA in Spodoptera frugiperda cells Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
 x * 33000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + sn-2-monoacylglycerol Mus musculus in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues CoA + diacylglycerol
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q91ZV4
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brown adipose tissue MGAT1 Mus musculus
-
kidney
-
 Mus musculus
-
liver MGAT1 Mus musculus
-
stomach
-
 Mus musculus
-
white adipose tissue MGAT1 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + sn-2-monoacylglycerol in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues Mus musculus CoA + diacylglycerol
-
 ?
arachidonoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-arachidonoyl-2-oleoylglycerol
-
 ?
arachidoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-arachidoyl-2-oleoylglycerol
-
 ?
lauroyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-lauroyl-2-oleoylglycerol
-
 ?
linoleoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-linoleoyl-2-oleoylglycerol
-
 ?
n-octanoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-octanoyl-2-oleoylglycerol
-
 ?
oleoyl-CoA + sn-1-monooleoylglycerol
-
 Mus musculus CoA + sn-1,3-dioleoylglycerol
-
 ?
oleoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + sn-1,2(2,3)-dioleoylglycerol
-
 ?
oleoyl-CoA + sn-3-monostearoylglycerol
-
 Mus musculus CoA + 1-oleoyl-3-stearoylglycerol
-
 ?
palmitoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1(3)-palmitoyl-2-oleoylglycerol
-
 ?
stearoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-stearoyl-2-oleolyglycerol
-
 ?

Subunits

Subunits Comment Organism
? x * 33000, SDS-PAGE Mus musculus