Cloned (Comment) | Organism |
---|---|
expression of MGAT2 in AV-12, COS-7 and CACO-2 cell | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + sn-2-monoacylglycerol | Mus musculus | the enzyme plays a predominant role in dietary fat absorption in the small intestine, where it catalyzes the first step of triacylglycerol resynthesis in enterocytes for chylomicron formation and secretion | CoA + diacylglycerol | - |
? | |
acyl-CoA + sn-2-monoacylglycerol | Mus musculus | MGAT2 may play an important role in dietary fat absorption | CoA + diacylglycerol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | - |
Mus musculus | - |
kidney | MGAT2 | Mus musculus | - |
kidney | highest expression of MGAT1 mRNA | Mus musculus | - |
liver | low expression of MGAT2 | Mus musculus | - |
skeletal muscle | low expression of MGAT2 | Mus musculus | - |
small intestine | - |
Mus musculus | - |
stomach | MGAT2 | Mus musculus | - |
stomach | highest expression of MGAT1 mRNA | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + sn-2-monoacylglycerol | the enzyme plays a predominant role in dietary fat absorption in the small intestine, where it catalyzes the first step of triacylglycerol resynthesis in enterocytes for chylomicron formation and secretion | Mus musculus | CoA + diacylglycerol | - |
? | |
acyl-CoA + sn-2-monoacylglycerol | MGAT2 may play an important role in dietary fat absorption | Mus musculus | CoA + diacylglycerol | - |
? | |
additional information | the enzyme catalyzes the acylation of rac-1-monoacylglycerol, sn-2-monoacylglycerol, and sn-3-monoacylglycerols, the enzyme prefers monoacylglycerols containing unsaturated fatty acyls | Mus musculus | ? | - |
? | |
oleoyl-CoA + sn-2-monooleoylglycerol | - |
Mus musculus | CoA + sn-1,2(2,3)-dioleoylglycerol | - |
? |