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Literature summary for 2.3.1.217 extracted from

  • Rodrigues, J.; Couto, M.; Ara๚jo, R.; Prather, K.; Kluskens, L.; Rodrigues, L.
    Hydroxycinnamic acids and curcumin production in engineered Escherichia coli using heat shock promoters (2017), Biochem. Eng. J., 125, 41-49 .
No PubMed abstract available

Application

Application Comment Organism
synthesis biosynthetic pathway of p-coumaric acid, caffeic acid and curcumin in Escherichia coli can be triggered by using heat shock promoters, suggesting its potential for the development of new industrial bioprocesses or even new bacterial therapies. p-Coumaric acid is successfully produced from tyrosine and caffeic acid produced either from tyrosine or p-coumaric acid using tyrosine ammonia lyase (TAL) from Rhodotorula glutinis, 4-coumarate 3-hydroxylase (C3H) from Saccharothrix espanaensis or cytochrome P450 CYP199A2 from Rhodopseudomonas palustris. The highest p-coumaric acid production obtained is 2.5 mM. Caffeic acid production reaches 0.370 mM. 0.017 mM cumin is produced using 4-coumarate-CoA ligase (4CL1) from Arabidopsis thaliana, diketide-CoA synthase (DCS) and curcumin synthase 1 (CURS1) from Curcuma longa Curcuma longa

Organism

Organism UniProt Comment Textmining
Curcuma longa C0SVZ6
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-

Synonyms

Synonyms Comment Organism
curcumin synthase 1
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Curcuma longa
CURS1
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Curcuma longa