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Literature summary for 2.3.1.212 extracted from

  • Abe, I.; Takahashi, Y.; Noguchi, H.
    Enzymatic formation of an unnatural C6-C5 aromatic polyketide by plant type III polyketide synthases (2002), Org. Lett., 4, 3623-3626.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-coumaroyl-CoA + malonyl-CoA + H2O Rheum palmatum
-
2 CoA + 4-hydroxybenzalacetone + 2 CO2
-
?

Organism

Organism UniProt Comment Textmining
Rheum palmatum Q94FV7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-coumaroyl-CoA + malonyl-CoA + H2O
-
Rheum palmatum 2 CoA + 4-hydroxybenzalacetone + 2 CO2
-
?
4-coumaroyl-CoA + methylmalonyl-CoA + H2O one-step decarboxylative condensation of the two substrates Rheum palmatum 2 CoA + 1-(4-hydroxyphenyl)pent-1-en-3-one + 2 CO2
-
?
additional information no activity with succinyl-CoA Rheum palmatum ?
-
?

Synonyms

Synonyms Comment Organism
bAS
-
Rheum palmatum

General Information

General Information Comment Organism
evolution the enzyme is a plant-specific type III polyketide synthase of the chalcone synthase (CHS) superfamily Rheum palmatum