BRENDA - Enzyme Database
show all sequences of 2.3.1.208

Phytoalexin formation in fire blight-infected apple

Chizzali, C.; Gaid, M.M.; Belkheir, A.K.; Beuerle, T.; Haensch, R.; Richter, K.; Flachowsky, H.; Peil, A; Hanke, M.-V.; Liu, B.; Beerhues, L.; Trees 2012, 1-8 (2012)
No PubMed abstract available

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
additional information
junctions between cortical parenchyma cells
Malus domestica
-
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
43000
-
x * 43000, BIS3, SDS-PAGE
Malus domestica
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
malonyl-CoA + 2-hydroxybenzoyl-CoA
Malus domestica
-
2 CoA + 4-hydroxycoumarin + CO2
-
-
?
malonyl-CoA + 2-hydroxybenzoyl-CoA
Sorbus aucuparia
-
2 CoA + 4-hydroxycoumarin + CO2
-
-
?
additional information
Malus domestica
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
?
-
-
-
additional information
Sorbus aucuparia
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
?
-
-
-
Organism
Organism
UniProt
Commentary
Textmining
Malus domestica
-
cv. Holsteiner Cox
-
Sorbus aucuparia
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
bark
BIS3, parenchyma of the bark
Malus domestica
-
cell culture
elicitor-treated cell cultures
Sorbus aucuparia
-
leaf
BIS2
Malus domestica
-
shoot
-
Malus domestica
-
stem
-
Malus domestica
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
malonyl-CoA + 2-hydroxybenzoyl-CoA
-
721091
Malus domestica
2 CoA + 4-hydroxycoumarin + CO2
-
-
-
?
malonyl-CoA + 2-hydroxybenzoyl-CoA
-
721091
Sorbus aucuparia
2 CoA + 4-hydroxycoumarin + CO2
-
-
-
?
additional information
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
721091
Malus domestica
?
-
-
-
-
additional information
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
721091
Sorbus aucuparia
?
-
-
-
-
Subunits
Subunits
Commentary
Organism
?
x * 43000, BIS3, SDS-PAGE
Malus domestica
Synonyms
Synonyms
Commentary
Organism
biphenyl synthase
-
Malus domestica
biphenyl synthase
-
Sorbus aucuparia
BIS
-
Malus domestica
BIS
-
Sorbus aucuparia
BIS3
-
Malus domestica
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
additional information
junctions between cortical parenchyma cells
Malus domestica
-
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
43000
-
x * 43000, BIS3, SDS-PAGE
Malus domestica
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
malonyl-CoA + 2-hydroxybenzoyl-CoA
Malus domestica
-
2 CoA + 4-hydroxycoumarin + CO2
-
-
?
malonyl-CoA + 2-hydroxybenzoyl-CoA
Sorbus aucuparia
-
2 CoA + 4-hydroxycoumarin + CO2
-
-
?
additional information
Malus domestica
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
?
-
-
-
additional information
Sorbus aucuparia
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
?
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
bark
BIS3, parenchyma of the bark
Malus domestica
-
cell culture
elicitor-treated cell cultures
Sorbus aucuparia
-
leaf
BIS2
Malus domestica
-
shoot
-
Malus domestica
-
stem
-
Malus domestica
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
malonyl-CoA + 2-hydroxybenzoyl-CoA
-
721091
Malus domestica
2 CoA + 4-hydroxycoumarin + CO2
-
-
-
?
malonyl-CoA + 2-hydroxybenzoyl-CoA
-
721091
Sorbus aucuparia
2 CoA + 4-hydroxycoumarin + CO2
-
-
-
?
additional information
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
721091
Malus domestica
?
-
-
-
-
additional information
for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule
721091
Sorbus aucuparia
?
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 43000, BIS3, SDS-PAGE
Malus domestica
Expression
Organism
Commentary
Expression
Malus domestica
BIS2 and BIS3 are not induced by phytoalexins, e.g. Erwinia amylovora, applicated to the shoot
additional information
Sorbus aucuparia
BIS is induced by elicitors in cell culture
up
General Information
General Information
Commentary
Organism
evolution
biphenyl synthase is a type III polyketide synthase
Malus domestica
evolution
biphenyl synthase is a type III polyketide synthase
Sorbus aucuparia
physiological function
BIS3 appears to catalyze the formation of phytoalexins in the transition zone, while BIS2 does not
Malus domestica
General Information (protein specific)
General Information
Commentary
Organism
evolution
biphenyl synthase is a type III polyketide synthase
Malus domestica
evolution
biphenyl synthase is a type III polyketide synthase
Sorbus aucuparia
physiological function
BIS3 appears to catalyze the formation of phytoalexins in the transition zone, while BIS2 does not
Malus domestica
Expression (protein specific)
Organism
Commentary
Expression
Malus domestica
BIS2 and BIS3 are not induced by phytoalexins, e.g. Erwinia amylovora, applicated to the shoot
additional information
Sorbus aucuparia
BIS is induced by elicitors in cell culture
up
Other publictions for EC 2.3.1.208
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721091
Chizzali
-
Phytoalexin formation in fire ...
Malus domestica, Sorbus aucuparia
Trees
2012
1-8
2012
-
-
-
-
-
-
-
-
1
-
1
4
-
2
-
-
-
-
-
5
-
-
4
1
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
4
-
-
-
-
-
5
-
-
4
1
-
-
-
-
-
-
-
-
2
3
3
2
-
-
706258
Liu
A novel 4-hydroxycoumarin bios ...
Sorbus aucuparia
Plant Mol. Biol.
72
17-25
2010
-
-
1
-
-
-
-
6
-
-
1
8
-
3
-
-
1
-
-
1
-
-
11
1
3
1
-
-
3
1
-
-
-
-
2
-
-
-
2
-
-
-
-
-
-
-
6
-
-
1
8
-
-
-
2
-
3
-
-
11
2
3
-
-
3
3
-
-
2
1
2
6
2
3
3
706131
Beerhues
Biosynthesis of biphenyls and ...
Sorbus aucuparia
Phytochemistry
70
1719-1727
2009
-
-
-
-
2
-
-
-
-
-
-
2
-
1
-
-
-
-
-
1
-
-
4
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
1
2
2
1
-
-