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Literature summary for 2.3.1.208 extracted from

  • Chizzali, C.; Gaid, M.M.; Belkheir, A.K.; Beuerle, T.; Haensch, R.; Richter, K.; Flachowsky, H.; Peil, A; Hanke, M.-V.; Liu, B.; Beerhues, L.
    Phytoalexin formation in fire blight-infected apple (2012), Trees, 2012, 1-8.
No PubMed abstract available

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information junctions between cortical parenchyma cells Malus domestica
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
x * 43000, BIS3, SDS-PAGE Malus domestica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malonyl-CoA + 2-hydroxybenzoyl-CoA Malus domestica
-
2 CoA + 4-hydroxycoumarin + CO2
-
?
malonyl-CoA + 2-hydroxybenzoyl-CoA Sorbus aucuparia
-
2 CoA + 4-hydroxycoumarin + CO2
-
?
additional information Malus domestica for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule ?
-
?
additional information Sorbus aucuparia for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule ?
-
?

Organism

Organism UniProt Comment Textmining
Malus domestica
-
cv. Holsteiner Cox
-
Sorbus aucuparia
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bark BIS3, parenchyma of the bark Malus domestica
-
cell culture elicitor-treated cell cultures Sorbus aucuparia
-
leaf BIS2 Malus domestica
-
shoot
-
Malus domestica
-
stem
-
Malus domestica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
malonyl-CoA + 2-hydroxybenzoyl-CoA
-
Malus domestica 2 CoA + 4-hydroxycoumarin + CO2
-
?
malonyl-CoA + 2-hydroxybenzoyl-CoA
-
Sorbus aucuparia 2 CoA + 4-hydroxycoumarin + CO2
-
?
additional information for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule Malus domestica ?
-
?
additional information for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule Sorbus aucuparia ?
-
?

Subunits

Subunits Comment Organism
? x * 43000, BIS3, SDS-PAGE Malus domestica

Synonyms

Synonyms Comment Organism
biphenyl synthase
-
Malus domestica
biphenyl synthase
-
Sorbus aucuparia
BIS
-
Malus domestica
BIS
-
Sorbus aucuparia
BIS3
-
Malus domestica

Expression

Organism Comment Expression
Malus domestica BIS2 and BIS3 are not induced by phytoalexins, e.g. Erwinia amylovora, applicated to the shoot additional information
Sorbus aucuparia BIS is induced by elicitors in cell culture up

General Information

General Information Comment Organism
evolution biphenyl synthase is a type III polyketide synthase Malus domestica
evolution biphenyl synthase is a type III polyketide synthase Sorbus aucuparia
physiological function BIS3 appears to catalyze the formation of phytoalexins in the transition zone, while BIS2 does not Malus domestica