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Literature summary for 2.3.1.20 extracted from

  • Zheng, Y.; Jin, Y.; Yuan, Y.; Feng, D.; Chen, L.; Li, D.; Zhou, P.
    Identification and function analysis of a type 2 diacylglycerol acyltransferase (DGAT2) from the endosperm of coconut (Cocos nucifera L.) (2019), Gene, 702, 75-82 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene CoDGAT2, sequence comparisons, recombinant expression in and complementation of Saccharomyces cerevisiae strain H1246 that is deficient in trinacylglycerol (TAG) production. Seed-specific overexpression of CoDGAT2 in Arabidopsis thaliana leads to a significant increase in the linoleic acid (C18:2) content (approximately 6%) compared to wild-type. In contrast, the proportions of eicosadienoic acid (C20:1) and arachidic acid (C20:0) are decreased, quantitative RT-PCR expression analysis Cocos nucifera

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + 1,2-diacyl-sn-glycerol Cocos nucifera
-
CoA + 1,2,3-triacylglycerol
-
?

Organism

Organism UniProt Comment Textmining
Cocos nucifera
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endosperm CoDGAT2 is highly expressed in coconut pulp approximately 7 months after pollination. CoDGAT2 is highly expressed in endosperm developmental stage 1, decreases significantly at stage 2, and is then restored to the same level as in stage 1 Cocos nucifera
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + 1,2-diacyl-sn-glycerol
-
Cocos nucifera CoA + 1,2,3-triacylglycerol
-
?
additional information the enzyme exhibits substrate preference for two unsaturated fatty acids (UFAs), palmitoleic acid (C16:1) and oleic acid (C18:1) Cocos nucifera ?
-
-

Synonyms

Synonyms Comment Organism
2 diacylglycerol acyltransferase
-
Cocos nucifera
CoDGAT2
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Cocos nucifera
DGAT2
-
Cocos nucifera

General Information

General Information Comment Organism
metabolism type 2 diacylglycerol acyltransferase (DGAT2) is one of the key enzymes involved in triacylglycerol (TAG) biosynthesis Cocos nucifera