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Literature summary for 2.3.1.20 extracted from

  • Parthasarathy, S.; Murari, R.; Crilly, K.S.; Baumann, W.J.
    Modulation of diacylglycerol acyltransferase by lysophosphatidylcholine and related monochain phospholipids (1981), Biochim. Biophys. Acta, 664, 249-254.
    View publication on PubMed
Search for more literature for 2.3.1.20

Activating Compound

Activating Compound Comment Organism Structure
1-acyl-sn-glycero-3-phosphocholine activation, at low concentrations, inhibition above 0.2 mM Rattus norvegicus
1-acyl-sn-glycero-3-phosphoethanolamine activation, to a lesser extent Rattus norvegicus
1-O-Hexadecylpropanediol-3-phosphocholine activation, low concentration, inhibitory at high concentration Rattus norvegicus
lysophosphatidylcholine activation at low concentrations, optimum at 0.075 mM, inhibitory above 0.2 mM Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
1-acyl-sn-glycero-3-phosphocholine activation, at low concentrations, inhibition above 0.2 mM Rattus norvegicus
1-O-Hexadecylpropanediol-3-phosphocholine activation, low concentration, inhibitory at high concentration Rattus norvegicus
lysophosphatidylcholine activation at low concentrations, optimum at 0.075 mM, inhibitory above 0.2 mM Rattus norvegicus
sodium taurocholate
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley
-
Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + 1,2-diacylglycerol
-
 Rattus norvegicus CoA + triacylglycerol
-
 ?
acyl-CoA + 1,2-diacylglycerol
-
 Rattus norvegicus Sprague-Dawley CoA + triacylglycerol
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
additional information
-
 assay at various temperatures from 24°C to 40°C Rattus norvegicus