Literature summary for 2.3.1.185 extracted from

Robins, R.J.; Bachmann, P.; Robinson, T.; Rhodes, M.J.; Yamada, Y.
The formation of 3alpha- and 3beta-acetoxytropanes by Datura stramonium transformed root cultures involves two acetyl-CoA-dependent acyltransferases (1991), FEBS Lett., 292, 293-297.

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Activating Compound

Activating Compound	Comment	Organism	Structure
EDTA	activates	Datura stramonium
tetraethyl diphosphite	activates	Datura stramonium

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.22	-	acetyl-CoA	-	Datura stramonium
0.24	-	Tropine	-	Datura stramonium

Organism

Organism	UniProt	Comment	Textmining
Datura stramonium	-	line D15/5	-

Purification (Commentary)

Purification (Comment)	Organism
-	Datura stramonium

Source Tissue

Source Tissue	Comment	Organism	Textmining
root	-	Datura stramonium	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.00002	-	-	Datura stramonium

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + tropine	-	Datura stramonium	CoA + O-acetyltropine	-	?

Synonyms

Synonyms	Comment	Organism
acetyI-CoA:tropine acyltransferase	-	Datura stramonium

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
9	-	-	Datura stramonium

pH Range

pH Minimum	pH Maximum	Comment	Organism
8	10	pH 7.0: less than 10% of maximal activity, pH 8.0: about 90% of maximal activity, pH 10.0: about 80% of maximal activity	Datura stramonium

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Release 2023.1 (January 2023)