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Literature summary for 2.3.1.184 extracted from

  • Niu, C.; Clemmer, K.M.; Bonomo, R.A.; Rather, P.N.
    Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii (2008), J. Bacteriol., 190, 3386-3392.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.184

Activating Compound

Activating Compound Comment Organism Structure
3-hydroxy-C12-HSL abaI is regulated by a positive-feedback loop involving self-produced acyl-homoserine lactone signals Acinetobacter baumannii

Application

Application Comment Organism
medicine Acinetobacter baumannii is an important nosocomial pathogen and can cause a variety of infections including wound infection, bloodstrem infection, ventilator-acquired pneumonia, and urinary tract infections Acinetobacter baumannii

Cloned(Commentary)

Cloned (Comment) Organism
the abaI gene is cloned into the pBluescript SK vector Acinetobacter baumannii

Protein Variants

Protein Variants Comment Organism
abaI_Km mutant mutant failed to produce any detectable acyl-homoserine lactone signals Acinetobacter baumannii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine Acinetobacter baumannii
-
 [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone
-
 ?

Organism

Organism UniProt Comment Textmining
Acinetobacter baumannii B0FLN1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine
-
 Acinetobacter baumannii [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone
-
 ?

Synonyms

Synonyms Comment Organism
AbaI
-
 Acinetobacter baumannii
acyl-homoserine-lactone synthase
-
 Acinetobacter baumannii
AHL synthase
-
 Acinetobacter baumannii
autoinducer synthase
-
 Acinetobacter baumannii