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Literature summary for 2.3.1.179 extracted from

  • Pidkowich, M.S.; Nguyen, H.T.; Heilmann, I.; Ischebeck, T.; Shanklin, J.
    Modulating seed beta-ketoacyl-acyl carrier protein synthase II level converts the composition of a temperate seed oil to that of a palm-like tropical oil (2007), Proc. Natl. Acad. Sci. USA, 104, 4742-4747.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.179

Application

Application Comment Organism
biotechnology modulating KASII activity is sufficient to convert the composition of a temperate seed oil into that of a palm-like tropical oil, overview Arabidopsis thaliana

Cloned(Commentary)

Cloned (Comment) Organism
gene FAB1 Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of KASII knockout mutants by T-DNA disruption, knockout alleles fab1-1 and fab1-2, strong seed-specific hairpin-RNAi reductions in FAB1 expression resulted in abortion of about 1/4 of the embryos in an apparent phenocopy of fab1-2 homozygosity, in less severe FAB1 hairpin-RNAi individuals, embryos developed normally and exhibited a 1:2:1 segregation ratio for palmitate accumulation, thus, early embryo development appears sensitive to elevated 16:0, whereas at later stages, up to 53% of 16:0, i.e. a 7-fold increase over wild-type levels, is tolerated, Fab1-1 mutant plants show about 60% of wild-type enzyme activity and about 17% palm-like oil accumulation compared to the wild-type plants, phenotypes, overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
 Arabidopsis thaliana 9507
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana KASII elongates 16:0-acyl carrier protein to 18:0-acyl carrier protein in the plastid, where it competes with three other enzymes at the first major branch point in fatty acid biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis sp.
-
-
-
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
seed
-
 Arabidopsis thaliana
-
seed modulation of Arabidopsis KASII levels is sufficient to convert its temperate oilseed composition to that of a palm-like tropical oil Arabidopsis sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information KASII elongates 16:0-acyl carrier protein to 18:0-acyl carrier protein in the plastid, where it competes with three other enzymes at the first major branch point in fatty acid biosynthesis Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
beta-ketoacyl-acyl carrier protein synthase II
-
 Arabidopsis thaliana
beta-ketoacyl-acyl-carrier protein synthase II
-
 Arabidopsis sp.
KASII
-
 Arabidopsis thaliana
KASII
-
 Arabidopsis sp.