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Literature summary for 2.3.1.179 extracted from
- Multiple forms of beta-ketoacyl-acyl carrier protein synthetase in Escherichia coli (1975), J. Biol. Chem., 250, 5289-5294.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| iodoacetamide | prior incubation of the enzymes with fatty acyl thioesters prevents inhibition | Escherichia coli |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.014 | - |
acetyl-[acyl-carrier protein] | pH 7.2 | Escherichia coli | |
| 0.017 | - |
cis-3-decenoyl-[acyl-carrier protein] | pH 7.2 | Escherichia coli | |
| 0.04 | - |
palmitoleoyl-[acyl-carrier protein] | pH 7.2 | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 76000 | - |
gel filtration | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P0AAI5 | - |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] | - |
Escherichia coli | acetoacetyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein] | - |
? | |
| cis-3-decenoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] | - |
Escherichia coli | ? + CO2 + [acyl-carrier protein] | - |
? | |
| palmitoleoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] | - |
Escherichia coli | cis-vaccenoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| beta-ketoacyl-ACP synthase II | - |
Escherichia coli |
| beta-ketoacyl-acyl carrier protein synthetase II | - |
Escherichia coli |
| FabF | - |
Escherichia coli |
| KAS II | - |
Escherichia coli |
| KASII | - |
Escherichia coli |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 43 | - |
t1/2: 81 min | Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 6.1 | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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