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Literature summary for 2.3.1.176 extracted from

  • Schroeder, F.; Atshaves, B.P.; McIntosh, A.L.; Gallegos, A.M.; Storey, S.M.; Parr, R.D.; Jefferson, J.R.; Ball, J.M.; Kier, A.B.
    Sterol carrier protein-2: new roles in regulating lipid rafts and signaling (2007), Biochim. Biophys. Acta, 1771, 700-718.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.176

Application

Application Comment Organism
pharmacology although SCP-2 was established as a protein that transfers cholesterol and phospholipids decades ago, recent findings with lipid rafts/caveolae and SCP-2 suggest that they may provide a conceptual link to metabolic processes that might be regulated through the respective signaling pathways Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
-
 Mus musculus

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-
peroxisome
-
 Mus musculus 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
13000
-
 SCP-2 Mus musculus
15000
-
 SCP-2 precursor Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA Mus musculus
-
 CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
intestine
-
 Mus musculus
-
liver
-
 Mus musculus
-
additional information highly expressed in tissues involved in cholesterol trafficking and oxidation Mus musculus
-
ovary
-
 Mus musculus
-
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA
-
 Mus musculus CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA
-
 ?

Synonyms

Synonyms Comment Organism
non-specific lipid transfer protein
-
 Mus musculus
nsLTP
-
 Mus musculus
propanoyl-CoA C-acyltransferase
-
 Mus musculus
SCP-2
-
 Mus musculus
sterol carrier protein-2
-
 Mus musculus