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Literature summary for 2.3.1.167 extracted from

  • Han, F.; Kang, L.Z.; Zeng, X.L.; Ye, Z.W.; Guo, L.Q.; Lin, J.F.
    Bioproduction of baccatin III, an advanced precursor of paclitaxol, with transgenic Flammulina velutipes expressing the 10-deacetylbaccatin III-10-O-acetyl transferase gene (2014), J. Sci. Food Agric., 94, 2376-2383.
    View publication on PubMed

Application

Application Comment Organism
synthesis transgenic Flammulina velutipes expressing the DBAT gene is able to produce baccatin III, an advanced precursor of paclitaxel Taxus chinensis

Organism

Organism UniProt Comment Textmining
Taxus chinensis
-
-
-
Taxus chinensis var. mairei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 10-deacetylbaccatin III
-
Taxus chinensis CoA + baccatin III catalyzes the acetylation of the C10 hydroxyl group of the advanced metabolite 10-deacetylbaccatin III to yield baccatin III, which is the immediate diterpenoid precursor of taxol ?
acetyl-CoA + 10-deacetylbaccatin III
-
Taxus chinensis var. mairei CoA + baccatin III catalyzes the acetylation of the C10 hydroxyl group of the advanced metabolite 10-deacetylbaccatin III to yield baccatin III, which is the immediate diterpenoid precursor of taxol ?

Synonyms

Synonyms Comment Organism
10-DAB
-
Taxus chinensis
DBAT
-
Taxus chinensis