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Literature summary for 2.3.1.164 extracted from

  • Garcia-Estrada, C.; Barreiro, C.; Jami, M.S.; Martin-Gonzalez, J.; Martin, J.F.
    The inducers 1,3-diaminopropane and spermidine cause the reprogramming of metabolism in Penicillium chrysogenum, leading to multiple vesicles and penicillin overproduction (2013), J. Proteomics, 85, 129-159.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Penicillium chrysogenum Q3HUS0
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Penicillium chrysogenum Wisconsin 54-1255 Q3HUS0
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Expression

Organism Comment Expression
Penicillium chrysogenum addition of either 1,3-diaminopropane or spermidine leads to a rearrangement of the proteome resulting in an overrepresentation of enzymes involved in the biosynthesis of valine and other precursors (e.g. coenzyme A) of penicillin and to the overrepresentation of the last enzyme of the penicillin pathway, isopenicillin N acyltransferase up