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Literature summary for 2.3.1.159 extracted from

  • Morita, H.; Kondo, S.; Kato, R.; Wanibuchi, K.; Noguchi, H.; Sugio, S.; Abe, I.; Kohno, T.
    Crystallization and preliminary crystallographic analysis of an acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata (2007), Acta Crystallogr. Sect. F, 63, 576-578.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Huperzia serrata

Crystallization (Commentary)

Crystallization (Comment) Organism
using the hanging-drop vapour-diffusion method Huperzia serrata

Organism

Organism UniProt Comment Textmining
Huperzia serrata
-
-
-

Purification (Commentary)

Purification (Comment) Organism
the recombinant protein by glutathione sepharose affinity column chromatography Huperzia serrata

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methoxycinnamoyl-CoA + 3 malonyl-CoA
-
Huperzia serrata 4-methoxy-2',4',6'-trihydroxychalcone + CoA + CO2
-
?
N-methylanthraniloyl-CoA + 3 malonyl-CoA
-
Huperzia serrata 1,3-dihydroxy-N-methylacridone + CoA + CO2
-
?

Synonyms

Synonyms Comment Organism
acridone synthase
-
Huperzia serrata
PKS1 type III polyketide synthase has 58% identity with acridone synthase from Ruta graveolens Huperzia serrata