The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum

Weid, M.; Ziegler, J.; Kutchan, T.M.; Proc. Natl. Acad. Sci. USA 101, 13957-13962 (2004)

Data extracted from this reference:

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

acetyl-CoA + salutaridinol

Papaver somniferum

involved in morphine biosynthesis

CoA + 7-O-acetylsalutaridinol

-

-

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

Substrate Product ID

acetyl-CoA + salutaridinol

-

657166

Papaver somniferum

CoA + 7-O-acetylsalutaridinol

-

-

-

?

acetyl-CoA + salutaridinol

involved in morphine biosynthesis

657166

Papaver somniferum

CoA + 7-O-acetylsalutaridinol

-

-

-

?

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

acetyl-CoA + salutaridinol

Papaver somniferum

involved in morphine biosynthesis

CoA + 7-O-acetylsalutaridinol

-

-

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

ID

acetyl-CoA + salutaridinol

-

657166

Papaver somniferum

CoA + 7-O-acetylsalutaridinol

-

-

-

?

acetyl-CoA + salutaridinol

involved in morphine biosynthesis

657166

Papaver somniferum

CoA + 7-O-acetylsalutaridinol

-

-

-

?

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Synonyms

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

755747

Madani

-

Enhanced thebaine and noscapi ...

Papaver bracteatum, Papaver bracteatum Lindl

Acta Physiol. Plant.

41

194

2019

-

-

-

-

-

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2

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1

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1

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-

-

-

-

1

-

-

1

-

-

737076

Fossati

Synthesis of morphinan alkaloi ...

Papaver somniferum

PLoS ONE

10

e0124459

2015

-

1

-

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-

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1

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-

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-

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-

743574

Fossati

Synthesis of morphinan alkalo ...

Papaver somniferum

PLoS ONE

10

e0124459

2015

-

-

1

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1

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1

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-

720707

Wijekoon

Systematic knockdown of morphi ...

Papaver somniferum

Plant J.

69

1052-1063

2012

-

-

1

-

1

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1

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2

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1

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1

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-

2

2

-

-

-

700683

Kempe

RNAi suppression of the morphi ...

Papaver somniferum

Phytochemistry

70

579-589

2009

-

-

1

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1

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5

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1

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1

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1

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1

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1

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2

2

-

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-

689455

Allen

Metabolic engineering of morph ...

Papaver somniferum

Plant Biotechnol. J.

6

22-30

2008

-

1

1

-

-

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4

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3

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1

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3

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1

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670561

Samanani

The role of phloem sieve eleme ...

Papaver somniferum

Plant J.

47

547-563

2006

-

-

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1

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657166

Weid

The roles of latex and the vas ...

Papaver somniferum

Proc. Natl. Acad. Sci. USA

101

13957-13962

2004

-

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4

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1

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660096

Facchini

Developmental and inducible ac ...

Papaver somniferum

Phytochemistry

64

177-186

2003

1

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5

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662108

Grothe

Molecular characterization of ...

Papaver somniferum

J. Biol. Chem.

276

30717-30723

2001

-

1

1

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4

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1

1

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7

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1

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3

1

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2

1

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1

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16324

Lenz

Acetyl coenzyme A:salutaridino ...

no activity in Papaver rhoeas, Papaver bracteatum, Papaver somniferum

J. Biol. Chem.

270

31091-31096

1995

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11

4

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1

1

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3

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1

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6

1

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6

1

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6

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6

1

1

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16325

Lenz

-

Closure of the oxide bridge in ...

Papaver sp.

Tetrahedron Lett.

35

3897-3900

1994

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