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Literature summary for 2.3.1.15 extracted from

  • Faris, R.; Fan, Y.Y.; De Angulo, A.; Chapkin, R.S.; deGraffenried, L.A.; Jolly, C.A.
    Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential for murine CD4(+) T cell metabolic activation (2014), Biochim. Biophys. Acta, 1842, 1475-1482.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.15

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + sn-glycerol 3-phosphate Mus musculus
-
 CoA + lysophosphatidic acid
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
helper T-lymphocyte CD4+ Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + sn-glycerol 3-phosphate
-
 Mus musculus CoA + lysophosphatidic acid
-
 ?

Synonyms

Synonyms Comment Organism
glycerol-3-phosphate acyltransferase-1
-
 Mus musculus
GPAT-1
-
 Mus musculus

General Information

General Information Comment Organism
malfunction enzyme deficiency results in altered or dysfunctional mitochondria Mus musculus
physiological function the enzyme is essential for the response to the increased metabolic demands associated with T cell activation Mus musculus