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Literature summary for 2.3.1.15 extracted from

  • Carroll, M.A.; Morris, P.E.; Grosjean, C.D.; Anzalone, T.; Haldar, D.
    Further distinguishing properties of mitochondrial and microsomal glycerophosphate acyltransferase and the transmembrane location of the mitochondrial enzyme (1982), Arch. Biochem. Biophys., 214, 17-25.
    View publication on PubMed
Search for more literature for 2.3.1.15

Activating Compound

Activating Compound Comment Organism Structure
Polymyxin B activation of mitochondrial enzyme, inhibition of microsomal enzyme Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Bromelain strong inhibition of microsomal enzyme Rattus norvegicus
deoxycholate
-
 Rattus norvegicus
additional information mitochondrial enzyme, not inhibited by bromelain, papain, pronase and trypsin Rattus norvegicus
papain strong inhibition of microsomal enzyme Rattus norvegicus
Polymyxin B 0.5 mg/ml, approx. 75% inhibition of microsomal enzyme, slight stimulation of mitochondrial enzyme Rattus norvegicus
Pronase strong inhibition of microsomal enzyme Rattus norvegicus
Triton X-100
-
 Rattus norvegicus
Trypsin 0.04 mg/ml, approx. 80% inhibition of microsomal enzyme within 3 min at 37°C, inhibition of the mitochondrial enzyme only in the presence of 0.05% deoxycholate or 0.1% Triton X-100 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-
mitochondrion
-
 Rattus norvegicus 5739
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male
-
Rattus norvegicus
-
 Sprague-Dawley strain
-
Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley strain
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Storage Stability

Storage Stability Organism
4-6°C, microsomal enzyme, t1/2: 4 h Rattus norvegicus
4-6°C, mitochondrial enzyme, 4 h, no loss of activity Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oleoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
oleoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus Sprague-Dawley CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus Sprague-Dawley CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?