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Literature summary for 2.3.1.147 extracted from

  • Neville, N.T.; Parton, J.; Harwood, J.L.; Jackson, S.K.
    The activities of monocyte lysophosphatidylcholine acyltransferase and coenzyme A-independent transacylase are changed by the inflammatory cytokines tumor necrosis factor alpha and interferon gamma (2005), Biochim. Biophys. Acta, 1733, 232-238.
    View publication on PubMed
Search for more literature for 2.3.1.147

Activating Compound

Activating Compound Comment Organism Structure
interferon gamma i.e. IFN-gamma, human, recombinant, increases enzyme activity in microsomes by about 100% Homo sapiens
Tumor necrosis factor alpha i.e. TNF-alpha, human, recombinant, 50% increase in enzyme activity within 30 min incubation of microsomes Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MM6 cell i.e. mono-mac 6, monocytic cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-alkyl-2-lyso-glyceryl phosphorylcholine + oleoyl-CoA
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
CoAIT
-
 Homo sapiens
Coenzyme A-independent transacylase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens