Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.140 extracted from

  • Zhuang, Y.; Jiang, J.; Bi, H.; Yin, H.; Liu, S.; Liu, T.
    Synthesis of rosmarinic acid analogues in Escherichia coli (2016), Biotechnol. Lett., 38, 619-627 .
    View publication on PubMed

Application

Application Comment Organism
synthesis production of rosmarinic acid analogues in Escherichia coli by expression of 4-coumarate: CoA ligase from Arabidopsis thaliana and rosmarinic acid synthase from Coleus blumei. Incubation of the recombinant strain with exogenously supplied phenyllactic acid and analogues, and coumaric acid and analogues as donor substrates leads to production of 18 compounds, including unnatural analogues Coleus scutellarioides

Organism

Organism UniProt Comment Textmining
Coleus scutellarioides
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-dihydroxyphenylpropanoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-(3,4-dihydroxyphenylpropanoyl)-3-(3,4-dihydroxyphenyl)lactate
-
?
3,4-dihydroxyphenylpropanoyl-CoA + 3-(4-hydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-(3,4-dihydroxyphenylpropanoyl)-3-(4-hydroxyphenyl)lactate
-
?
3,4-dihydroxyphenylpropanoyl-CoA + 3-phenyllactate
-
Coleus scutellarioides CoA + 2-O-(3,4-dihydroxyphenylpropanoyl)-3-phenyllactate
-
?
4-coumaroyl-CoA + 3-(3,4-dihydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-(4-coumaroyl)-3-(3,4-dihydroxyphenyl)lactate
-
?
4-coumaroyl-CoA + 3-(4-hydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-(4-coumaroyl)-3-(4-hydroxyphenyl)lactate
-
?
4-coumaroyl-CoA + mandelate
-
Coleus scutellarioides CoA + 2-O-(4-coumaroyl)-3-phenyllactate
-
?
4-coumaroyl-CoA + phenyllactate
-
Coleus scutellarioides CoA + 2-O-(4-coumaroyl)-3-phenyllactate
-
?
4-coumaroyl-CoA + tyrosol
-
Coleus scutellarioides CoA + 2-O-(4-coumaroyl)tyrosol
-
?
4-hydroxyphenylpropanoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-(4-hydroxyphenylpropanoyl)-3-(3,4-dihydroxyphenyl)lactate
-
?
4-hydroxyphenylpropanoyl-CoA + 3-(4-hydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-(4-hydroxyphenylpropanoyl)-3-(4-hydroxyphenyl)lactate
-
?
4-hydroxyphenylpropanoyl-CoA + 3-phenyllactate
-
Coleus scutellarioides CoA + 2-O-(4-hydroxyphenylpropanoyl)-3-phenyllactate
-
?
4-hydroxyphenylpropanoyl-CoA + mandelate
-
Coleus scutellarioides CoA + 2-O-(4-hydroxyphenylpropanoyl)mandelate
-
?
4-hydroxyphenylpropanoyl-CoA + tyrosol
-
Coleus scutellarioides CoA + 2-O-(4-hydroxyphenylpropanoyl)tyrosol
-
?
caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate
-
Coleus scutellarioides CoA + rosmarinate
-
?
caffeoyl-CoA + 3-(4-hydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-caffeoyl-3-(4-hydroxyphenyl)lactate
-
?
caffeoyl-CoA + mandelate
-
Coleus scutellarioides CoA + 2-O-caffeoylmandelate
-
?
caffeoyl-CoA + phenyllactate
-
Coleus scutellarioides CoA + 2-O-caffeoyl-3-phenyllactate
-
?
caffeoyl-CoA + tyrosol
-
Coleus scutellarioides CoA + 2-O-caffeoyltyrosol
-
?
feruloyl-CoA + 3-(3,4-dihydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-feruloyl-3-(3,4-dihydroxyphenyl)lactate
-
?
feruloyl-CoA + 3-(4-hydroxyphenyl)lactate
-
Coleus scutellarioides CoA + 2-O-feruloyl-3-(4-hydroxyphenyl)lactate
-
?
feruloyl-CoA + 3-phenyllactate
-
Coleus scutellarioides CoA + 2-O-feruloyl-3-(4-hydroxyphenyl)lactate
-
?