Cloned (Comment) | Organism |
---|---|
pYES2 plasmid containing the wild-type and the double mutant H131A/H340A of COT expressed in Saccharomyces cerevisiae | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
etomoxir | hypoglycaemia-inducing drug, double mutant H131A/H340A is insensitive to etomoxir | Rattus norvegicus | |
malonyl-CoA | double mutant H131A/H340A is insensitive to malonyl-CoA | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
decanoyl-CoA | recombinant enzyme expressed in Saccharomyces cerevisiae pYESCOTwt | Rattus norvegicus | |
0.013 | - |
decanoyl-CoA | recombinant enzyme expressed in Saccharomyces cerevisiae pYESCOTH340A/H131 | Rattus norvegicus | |
0.172 | - |
L-carnitine | recombinant enzyme expressed in Saccharomyces cerevisiae pYESCOTwt | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisome | - |
Rattus norvegicus | 5777 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | Rattus norvegicus | - |
acyl-L-carnitine + CoA | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | - |
Rattus norvegicus | acyl-L-carnitine + CoA | - |
r | |
decanoyl-CoA + L-carnitine | - |
Rattus norvegicus | L-decanoyl-L-carnitine + CoA | - |
r | |
decanoyl-L-carnitine + CoA | - |
Rattus norvegicus | decanoyl-CoA + L-carnitine | - |
r |