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Literature summary for 2.3.1.133 extracted from

  • Hoffmann, L.; Maury, S.; Martz, F.; Geoffroy, P.; Legrand, M.
    Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism (2003), J. Biol. Chem., 278, 95-103.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Nicotiana tabacum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.05
-
caffeoyl-CoA
-
Nicotiana tabacum
0.07
-
quinate
-
Nicotiana tabacum
0.35
-
feruloyl-CoA
-
Nicotiana tabacum
0.6
-
4-coumaroyl-CoA
-
Nicotiana tabacum
0.75
-
shikimate
-
Nicotiana tabacum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-coumaroyl-CoA + shikimate Nicotiana tabacum enzyme appears to play a critical role in the phenylpropanoid pathway, both upstream and downstream of the 3-hydroxylation step CoA + 5-O-(4-coumaroyl)shikimate
-
?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum Q8GSM7
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Nicotiana tabacum

Source Tissue

Source Tissue Comment Organism Textmining
stem
-
Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-coumaroyl-CoA + quinate
-
Nicotiana tabacum CoA + 4-coumaroylquinate
-
r
4-coumaroyl-CoA + shikimate
-
Nicotiana tabacum CoA + 5-O-(4-coumaroyl)shikimate
-
r
4-coumaroyl-CoA + shikimate enzyme appears to play a critical role in the phenylpropanoid pathway, both upstream and downstream of the 3-hydroxylation step Nicotiana tabacum CoA + 5-O-(4-coumaroyl)shikimate
-
?
caffeoyl-CoA + shikimate
-
Nicotiana tabacum CoA + 5-O-caffeoylshikimate
-
r
feruloyl-CoA + shikimate
-
Nicotiana tabacum CoA + 5-O-feruloylshikimate
-
r
additional information no substrate: anthranilate, glucose, malate, tyramine, spermidine, spermine, putrescine, agmatine, benzyl alcohol Nicotiana tabacum ?
-
?