BRENDA - Enzyme Database show
show all sequences of 2.3.1.110

Production of coumaroylserotonin and feruloylserotonin in transgenic rice expressing pepper hydroxycinnamoyl-coenzyme a:Serotonin N-(hydroxycinnamoyl)transferase

Jang, S.M.; Ishihara, A.; Back, K.; Plant Physiol. 135, 346-356 (2004)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
tyramine
10-50 mM
Capsicum annuum
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0035
-
feruloyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.0127
-
caffeoyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.0233
-
4-Coumaroyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.0319
-
cinnamoyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.073
-
serotonin
pH 8.5, 30°C
Capsicum annuum
0.721
-
dopamine
pH 8.5, 30°C
Capsicum annuum
0.848
-
tryptamine
pH 8.5, 30°C
Capsicum annuum
1.165
-
tyramine
pH 8.5, 30°C
Capsicum annuum
1.389
-
Phenylethylamine
pH 8.5, 30°C
Capsicum annuum
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Capsicum annuum
-
expression in Oryza sativa
-
Purification (Commentary)
Commentary
Organism
recombinant protein
Capsicum annuum
Source Tissue
Source Tissue
Commentary
Organism
Textmining
root
-
Capsicum annuum
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-coumaroyl-CoA + tyramine
tyramine at 19% the rate of phenylethylamine
660244
Capsicum annuum
CoA + N-(4-coumaroyl)tyramine
-
-
-
?
caffeoyl-CoA + serotonin
serotonin at 22% the rate of phenylethylamine
660244
Capsicum annuum
CoA + N-caffeoylserotonin
-
-
-
?
caffeoyl-CoA + tryptamine
tryptamine at 17% the rate of phenylethylamine
660244
Capsicum annuum
CoA + N-caffeoyltryptamine
-
-
-
?
caffeoyl-CoA + tyramine
caffeoyl-CoA at 89% the rate of 4-coumaroyl-CoA
660244
Capsicum annuum
CoA + N-caffeoyltyramine
-
-
-
?
cinnamoyl-CoA + tyramine
cinnamoyl-CoA at 66% the rate of 4-coumaroyl-CoA
660244
Capsicum annuum
CoA + cinnamoyltyramine
-
-
-
?
feruloyl-CoA + dopamine
feruloyl-CoA at 20% the rate of 4-coumaroyl-CoA, dopamine at 27% the rate of phenylethylamine
660244
Capsicum annuum
CoA + feruloyldopamine
-
-
-
?
feruloyl-CoA + phenethylamine
-
660244
Capsicum annuum
CoA + feruloylphenethylamine
-
-
-
?
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
tyramine
10-50 mM
Capsicum annuum
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0035
-
feruloyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.0127
-
caffeoyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.0233
-
4-Coumaroyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.0319
-
cinnamoyl-CoA
pH 8.5, 30°C
Capsicum annuum
0.073
-
serotonin
pH 8.5, 30°C
Capsicum annuum
0.721
-
dopamine
pH 8.5, 30°C
Capsicum annuum
0.848
-
tryptamine
pH 8.5, 30°C
Capsicum annuum
1.165
-
tyramine
pH 8.5, 30°C
Capsicum annuum
1.389
-
Phenylethylamine
pH 8.5, 30°C
Capsicum annuum
Purification (Commentary) (protein specific)
Commentary
Organism
recombinant protein
Capsicum annuum
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
root
-
Capsicum annuum
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-coumaroyl-CoA + tyramine
tyramine at 19% the rate of phenylethylamine
660244
Capsicum annuum
CoA + N-(4-coumaroyl)tyramine
-
-
-
?
caffeoyl-CoA + serotonin
serotonin at 22% the rate of phenylethylamine
660244
Capsicum annuum
CoA + N-caffeoylserotonin
-
-
-
?
caffeoyl-CoA + tryptamine
tryptamine at 17% the rate of phenylethylamine
660244
Capsicum annuum
CoA + N-caffeoyltryptamine
-
-
-
?
caffeoyl-CoA + tyramine
caffeoyl-CoA at 89% the rate of 4-coumaroyl-CoA
660244
Capsicum annuum
CoA + N-caffeoyltyramine
-
-
-
?
cinnamoyl-CoA + tyramine
cinnamoyl-CoA at 66% the rate of 4-coumaroyl-CoA
660244
Capsicum annuum
CoA + cinnamoyltyramine
-
-
-
?
feruloyl-CoA + dopamine
feruloyl-CoA at 20% the rate of 4-coumaroyl-CoA, dopamine at 27% the rate of phenylethylamine
660244
Capsicum annuum
CoA + feruloyldopamine
-
-
-
?
feruloyl-CoA + phenethylamine
-
660244
Capsicum annuum
CoA + feruloylphenethylamine
-
-
-
?
Other publictions for EC 2.3.1.110
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
736840
Campos
Transgenic tomato plants overe ...
Solanum lycopersicum
Mol. Plant Microbe Interact.
27
1159-1169
2014
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5
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1
1
-
-
-
720789
Landmann
Substrate promiscuity of a ros ...
Lavandula angustifolia
Planta
234
305-320
2011
-
-
1
-
-
-
-
11
1
-
1
1
-
1
-
-
1
-
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1
-
1
8
1
1
-
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1
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1
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11
1
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1
1
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1
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1
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1
8
1
1
-
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-
1
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-
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-
702823
Kang
Production of plant-specific t ...
Capsicum annuum
Biotechnol. Lett.
31
1469-1475
2009
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-
-
-
-
-
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-
1
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4
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1
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-
-
-
-
702831
Park
Endosperm-specific expression ...
Capsicum annuum
Biotechnol. Lett.
31
911-915
2009
-
1
1
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
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-
-
-
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-
-
1
1
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-
1
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-
1
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
673815
Niehl
-
Systemic Potato virus X infect ...
Solanum tuberosum
Funct. Plant Biol.
33
593-604
2006
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
1
-
-
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-
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1
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1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
676598
Kang
Functional analysis of the ami ...
Capsicum annuum
Plant Physiol.
140
704-715
2006
-
-
1
-
3
-
-
8
-
-
1
-
-
1
-
-
-
-
-
1
-
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
8
-
-
1
-
-
-
-
-
-
1
-
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
660324
Hagel
Elevated tyrosine decarboxylas ...
Nicotiana tabacum
Planta
221
904-914
2005
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
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1
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1
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1
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1
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1
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-
-
-
-
-
-
-
-
-
-
-
660244
Jang
Production of coumaroylseroton ...
Capsicum annuum
Plant Physiol.
135
346-356
2004
-
-
-
-
-
-
1
9
-
-
-
-
-
3
-
-
1
-
-
1
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
9
-
-
-
-
-
-
-
1
-
1
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486128
Back
Cloning and characterization o ...
Capsicum annuum
Plant Cell Physiol.
42
475-481
2001
-
-
1
-
-
-
-
-
-
-
1
1
-
5
-
-
1
-
-
5
-
-
6
-
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-
-
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-
1
-
-
-
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-
-
-
-
-
-
1
1
-
-
-
1
-
5
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486131
Negrel
L-Tyrosine beta-naphthylamide ...
Nicotiana tabacum, Solanum tuberosum
Phytochemistry
56
523-527
2001
-
-
-
-
-
-
8
-
-
-
-
-
-
4
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
8
8
-
-
-
-
-
-
-
-
2
-
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-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486130
Ishihara
Induction of N-hydroxycinnamoy ...
Zea mays
Biosci. Biotechnol. Biochem.
64
1025-1031
2000
-
-
-
-
-
-
2
8
-
-
1
1
-
2
-
-
1
-
-
1
1
-
7
-
-
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2
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8
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1
1
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1
-
1
1
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486129
Farmer
Identification and characteriz ...
Nicotiana tabacum
Eur. J. Biochem.
263
686-694
1999
-
-
1
-
-
-
3
-
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2
1
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1
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1
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2
1
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1
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3
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2
1
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1
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2
1
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-
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-
-
-
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-
-
-
486133
Schmidt
Cloning and expression of a po ...
Solanum tuberosum
J. Biol. Chem.
274
4273-4280
1999
-
-
1
-
-
-
-
2
-
-
2
1
-
4
-
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1
-
-
-
-
-
9
-
-
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-
-
-
-
-
-
-
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-
1
-
-
-
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2
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2
1
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-
1
-
-
-
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486134
Yu
Purification, characterization ...
Papaver somniferum
Planta
209
33-44
1999
-
-
-
-
-
-
3
6
-
-
2
1
-
1
-
-
1
-
-
4
1
3
5
1
-
-
-
-
1
1
-
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-
-
-
-
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-
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-
3
-
6
-
-
2
1
-
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1
-
4
1
3
5
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
486132
Negrel
Purification, characterization ...
Nicotiana tabacum
Eur. J. Biochem.
247
1127-1135
1997
1
-
-
-
-
-
11
12
-
-
2
1
-
2
-
-
1
1
-
-
1
-
13
1
-
-
-
-
-
-
-
-
9
-
-
1
-
-
-
-
-
-
-
11
9
12
-
-
2
1
-
-
-
1
-
-
1
-
13
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486127
Fleurence
-
Partial purification of tyrami ...
Nicotiana tabacum
Phytochemistry
28
733-736
1989
-
-
-
-
-
2
2
4
-
-
-
1
-
1
1
-
1
-
-
1
1
2
6
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
4
-
-
-
1
-
1
-
1
-
1
1
2
6
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
486126
Negrel
-
The biosynthesis of feruloylty ...
Nicotiana tabacum
Phytochemistry
23
2797-2801
1984
-
-
-
-
-
1
-
6
1
1
1
1
-
1
1
-
1
-
-
1
-
1
14
-
1
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
6
1
1
1
1
-
1
-
1
-
1
-
1
14
-
1
-
-
-
4
1
-
-
-
-
-
-
-
-