Any feedback?
Literature summary for 2.3.1.105 extracted from
- The potential for platelet-activating factor synthesis in brain: properties of cholinephosphotransferase and 1-alkyl-sn-glycero-3-phosphate acetyltransferase in microsomal fractions of immature rabbit cerebral cortex (1993), Biochim. Biophys. Acta, 1170, 157-164.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 1-alkyl-sn-glycero-3-phosphocholine | small increase of activity | Oryctolagus cuniculus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | - |
Oryctolagus cuniculus | |
| additional information | not inhibited by 1-alkyl-sn-glycero-3-phosphocholine, 1-alkyl-sn-glycero-3-phosphocholine | Oryctolagus cuniculus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.11 | - |
acetyl-CoA | apparent Km for subcellular fraction R | Oryctolagus cuniculus | |
| 0.137 | - |
acetyl-CoA | apparent Km for subcellular fraction P3 | Oryctolagus cuniculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cell body | brain | Oryctolagus cuniculus | 44297 | - |
| microsome | - |
Oryctolagus cuniculus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Na+ | activity appears maximal in the presence of NaF | Oryctolagus cuniculus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate | Oryctolagus cuniculus | - |
CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| isolation of four subcellular fractions: S, R and P3 from cerebral cortices and P from nerve cell bodies | Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebral cortex | - |
Oryctolagus cuniculus | - |
| nerve | brain | Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate | - |
Oryctolagus cuniculus | CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate | - |
? | |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 9 | subcellular fractions R and P3 | Oryctolagus cuniculus |
| 8.4 | 9 | subcellular fractions P | Oryctolagus cuniculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
