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Literature summary for 2.2.1.6 extracted from

  • Kalme, S.; Pham, C.; Gedi, V.; Le, D.; Choi, J.; Kim, S.; Yoon, M.
    Inhibitors of Bacillus anthracis acetohydroxyacid synthase (2008), Enzyme Microb. Technol., 43, 270-275.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
chlorimuronethyl noncompetitive, lowest total interaction energy and highest MolDock score of 140054 kcal/mol and -141.52, respectively, of the compounds analyzed Bacillus anthracis
imazapyr
-
Bacillus anthracis
imazaquin uncompetitive Bacillus anthracis
metsulfuronmethyl
-
Bacillus anthracis
pyrazosulfuronethyl
-
Bacillus anthracis
sulfometuronmethyl
-
Bacillus anthracis
thifensulfuronmethyl
-
Bacillus anthracis

Organism

Organism UniProt Comment Textmining
Bacillus anthracis
-
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00697
-
37°C Bacillus anthracis imazaquin
0.007
-
37°C Bacillus anthracis chlorimuronethyl
0.01
-
37°C Bacillus anthracis sulfometuronmethyl