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Literature summary for 2.2.1.12 extracted from

  • Kasparyan, E.; Richter, M.; Dresen, C.; Walter, L.S.; Fuchs, G.; Leeper, F.J.; Wacker, T.; Andrade, S.L.; Kolter, G.; Pohl, M.; Mueller, M.
    Asymmetric Stetter reactions catalyzed by thiamine diphosphate-dependent enzymes (2014), Appl. Microbiol. Biotechnol., 98, 9681-9690.
    View publication on PubMed
Search for more literature for 2.2.1.12

Organism

Organism UniProt Comment Textmining
Serratia marcescens Q5W251
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + (3E)-4-(4-chlorophenyl)but-3-en-2-one 39% conversion. (3R)-3-(4-Chlorophenyl)hexane-2,5-dione is produced with 75% enantiomeric excess Serratia marcescens (3R)-3-(4-chlorophenyl)hexane-2,5-dione + CO2
-
 ?
pyruvate + (3E)-4-(furan-2-yl)but-3-en-2-one 11% conversion Serratia marcescens 3-(furan-2-yl)hexane-2,5-dione + CO2
-
 ?
pyruvate + (3E)-4-phenylbut-3-en-2-one 10% conversion. (3R)-3-Phenylhexane-2,5-dione is produced with 82-95% enantiomeric excess Serratia marcescens (3R)-3-phenylhexane-2,5-dione + CO2
-
 ?
pyruvate + (3E)-non-3-en-2-one 37% conversion. (3S)-3-pentylhexane-2,5-dione is produced with more than 99% enantiomeric excess Serratia marcescens (3S)-3-pentylhexane-2,5-dione + CO2
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 ?
pyruvate + but-3-en-2-one 8% conversion Serratia marcescens hexane-2,5-dione + CO2
-
 ?
pyruvate + S-[2-(acetylamino)ethyl] (2E)-oct-2-enethioate 75% conversion Serratia marcescens S-[2-(acetylamino)ethyl] 3-acetyloctanethioate + CO2
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 ?

Synonyms

Synonyms Comment Organism
pigD
-
 Serratia marcescens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Serratia marcescens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Serratia marcescens