Literature summary for 2.2.1.1 extracted from

Krockenberger, M.; Honig, A.; Rieger, L.; Coy, J.F.; Sutterlin, M.; Kapp, M.; Horn, E.; Dietl, J.; Kammerer, U.
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases (2007), Int. J. Gynecol. Cancer, 17, 101-106.

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Application

Application	Comment	Organism
medicine	TKTL1 plays a crucial role in ovarian cancer metabolism and its expression predicts poor prognosis. TKTL1 could thus have a possible value as target for nontoxic antitumoral therapeutic approaches especially in advanced ovarian cancer, a disease where really efficient treatment options are limited	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	mucinous ovarian carcinoma tissue and borderline tumor tissue	Homo sapiens	-
ovarian serous carcinoma cell	significantly elevated expression of TKTL1 in serous papillary carcinomas in comparison to mucinous carcinomas, borderline tumors, and normal control ovarian tissue, which correlates with poor prognostic parameters	Homo sapiens	-
ovary	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
TKTL1	-	Homo sapiens
transketolase-like 1	-	Homo sapiens

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Release 2023.1 (January 2023)