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Literature summary for 2.2.1.1 extracted from

  • Warnock, L.G.; Prudhomme, C.R.
    The isolation and preliminary characterization of apotransketolase from human erythrocytes (1982), Biochem. Biophys. Res. Commun., 106, 719-723.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0004
-
thiamine diphosphate in the presence of Mg2+ Homo sapiens
0.18
-
D-xylulose 5-phosphate (+ D-ribose 5-phosphate) Homo sapiens
0.3
-
D-ribose 5-phosphate cosubstrate D-xylulose 5-phosphate Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ no exogenous Mg2+-addition necessary Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-xylulose 5-phosphate + D-ribose 5-phosphate Homo sapiens
-
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-

Storage Stability

Storage Stability Organism
4°C, at least 16 days Homo sapiens
room temperature, after 13 days at 4°C, at least 4 h stable Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Homo sapiens sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6 7.8
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
thiamine diphosphate not thiamine, thiamine mono-or triphosphate Homo sapiens